The impact of life stress on hallmarks of aging and accelerated senescence: Connections in sickness and in health
CE Lyons, M Razzoli, A Bartolomucci - Neuroscience & Biobehavioral …, 2023 - Elsevier
Chronic stress is a risk factor for numerous aging-related diseases and has been shown to
shorten lifespan in humans and other social mammals. Yet how life stress causes such a …
shorten lifespan in humans and other social mammals. Yet how life stress causes such a …
Aging biomarkers and the brain
Quantifying biological aging is critical for understanding why aging is the primary driver of
morbidity and mortality and for assessing novel therapies to counter pathological aging. In …
morbidity and mortality and for assessing novel therapies to counter pathological aging. In …
[HTML][HTML] Precision and personalized medicine: What their current definition says and silences about the model of health they promote. Implication for the development …
C Delpierre, T Lefèvre - Frontiers in Sociology, 2023 - frontiersin.org
The US National Human Genome Research Institute defines precision medicine as
follows:“Precision medicine (generally considered analogous to personalized medicine or …
follows:“Precision medicine (generally considered analogous to personalized medicine or …
[HTML][HTML] Psychological and biological resilience modulates the effects of stress on epigenetic aging
Our society is experiencing more stress than ever before, leading to both negative
psychiatric and physical outcomes. Chronic stress is linked to negative long-term health …
psychiatric and physical outcomes. Chronic stress is linked to negative long-term health …
Social relationships and epigenetic aging in older adulthood: Results from the Health and Retirement Study
Growing evidence suggests that social relationship quality can influence age-related health
outcomes, although how the quality of one's relationships directly relates to the underlying …
outcomes, although how the quality of one's relationships directly relates to the underlying …
Association of race and poverty status with DNA methylation–based age
Importance The Dunedin Pace of Aging Calculated From the Epigenome (DunedinPACE)
measure is a newly constructed DNA methylation (DNAm) biomarker associated with …
measure is a newly constructed DNA methylation (DNAm) biomarker associated with …
[HTML][HTML] How can early life adversity still exert an effect decades later? A question of timing, tissues and mechanisms
Exposure to any number of stressors during the first 1000 days from conception to age 2
years is important in shaping an individual's life trajectory of health and disease. Despite the …
years is important in shaping an individual's life trajectory of health and disease. Despite the …
[HTML][HTML] Longitudinal effects of choir singing on aging cognition and wellbeing: a two-year follow-up study
E Pentikäinen, L Kimppa, A Pitkäniemi… - Frontiers in human …, 2023 - frontiersin.org
Introduction While increasing evidence points toward the benefits of musical activities in
promoting cognitive and emotional well-being in older adults, more longitudinal studies are …
promoting cognitive and emotional well-being in older adults, more longitudinal studies are …
Contextual modifiers of healthspan, lifespan, and epigenome in mice under chronic social stress
Sustained life stress and low socioeconomic status are among the major causes of aging-
related diseases and decreased life expectancy. Experimental rodent models can help to …
related diseases and decreased life expectancy. Experimental rodent models can help to …
Prenatal maternal stress is associated with site-specific and age acceleration changes in maternal and newborn DNA methylation
Prenatal maternal stress has a negative impact on child health but the mechanisms through
which maternal stress affects child health are unclear. Epigenetic variation, such as DNA …
which maternal stress affects child health are unclear. Epigenetic variation, such as DNA …