Acute pancreatitis (AP) is a complex inflammatory disease caused by multiple etiologies, the
pathogenesis of which has not been fully elucidated. Oxidative stress is important for the …

Pancreatic cancer has one of the highest mortality rates among cancers, and a combination
of nab-paclitaxel with gemcitabine remains the cornerstone of first-line therapy. However …

Chemically modified steroids have a long history as anti-neoplastic drugs. Incorporation of a
lactone moiety in the steroid nucleus, as in previously obtained 3β-acetoxy-17-oxa-17a …

Severe acute pancreatitis (AP) is a life-threatening pancreatic inflammatory disease with a
high mortality rate (∼ 40%). Existing pharmaceutical therapies in development or in clinical …

Background Flavonoids may help ameliorate the incidence of the major causes of tumor-
related mortality, such as pancreatic ductal adenocarcinoma (PDAC) and lung cancer, which …

Human islet amyloid polypeptide (hIAPP or amylin) is a hormone co-secreted with insulin by
pancreatic β-cells, and is the main component of islet amyloid. Islet amyloid is found in the …

Abstract Currently, Non-Hodgkin Lymphoma (NHL) constitutes 85–90% of all lymphomas.
Clinical treatment of NHL is based on the “4-drug regimen” known as CHOP …

The current scenario has seen many transformative changes in target-based drug delivery
system. In this direction, encapsulation of medicines in nanoparticles has almost …

S100P, a member of the S100 calcium-binding protein family, is closely associated with
abnormal proliferation, invasion, and metastasis of various cancers. However, its role in the …

Pancreatic adenocarcinoma, a devastating disease, has the worst cancer prognosis in
humans. It often develops resistance to common chemotherapy medications, such as …