Free radical cyclizations involving nitrogen

AG Fallis, IM Brinza - Tetrahedron, 1997 - Elsevier
TEXRAHEDRON REPORT NUMBER 436 Page 1 Terrahedron, Vol. 53, No. 52, pp. 17543-17594,
1997 0 1997 Elsevier Science Ltd All rights reserved. Printed tn Great Britain PII: SOO40-4020(97) …

Addition of carbon-centered radicals to imines and related compounds

GK Friestad - Tetrahedron, 2001 - Elsevier
Imines (azomethines), iminium salts, and related compounds have been used as
electrophiles for ionic bond constructions (eg in the Mannich reaction) for many years, but …

SnAP reagents for the one-step synthesis of medium-ring saturated N-heterocycles from aldehydes

CVT Vo, MU Luescher, JW Bode - Nature chemistry, 2014 - nature.com
Interest in saturated N-heterocycles as scaffolds for the synthesis of bioactive molecules is
increasing. Reliable and predictable synthetic methods for the preparation of these …

Olefin amine (OLA) reagents for the synthesis of bridged bicyclic and spirocyclic saturated N-heterocycles by catalytic hydrogen atom transfer (HAT) reactions

YY Wang, JW Bode - Journal of the American Chemical Society, 2019 - ACS Publications
Spiro-and bridged bicyclic structures are in demand for their sp3-rich frameworks that offer
unique physiochemical properties and precisely positioned substituent groups. In order to …

Microwave-Promoted Syntheses of Quinazolines and Dihydroquinazolines from 2-Aminoarylalkanone O-Phenyl Oximes

F Portela-Cubillo, JS Scott… - The Journal of organic …, 2009 - ACS Publications
A wide range of biologically active compounds contain the quinazoline ring system. A new
free-radical-based method of making functionalized quinazolines is described, which relies …

Radical kinetics and clocks

M Newcomb - Encyclopedia of Radicals in Chemistry, Biology …, 2012 - Wiley Online Library
An overview of radical kinetics is presented, with an emphasis on competition kinetic
methods that can be achieved in most laboratories without special equipment. Methods for …

Asymmetric synthesis of α-amino acids based on carbon radical addition to glyoxylic oxime ether

H Miyabe, C Ushiro, M Ueda… - The Journal of Organic …, 2000 - ACS Publications
The first asymmetric synthesis of α-amino acids based on diastereoselective carbon radical
addition to glyoxylic imine derivatives is reported. The addition of an isopropyl radical …

Diethylzinc: A chain-transfer agent in intermolecular radical additions. A parallel with triethylborane

MP Bertrand, L Feray, R Nouguier… - The Journal of Organic …, 1999 - ACS Publications
In the presence of oxygen, diethylzinc can be used to promote radical additions to CN bond
containing radical acceptors and to enones. In these reactions, it plays at the same time the …

2-(Aminoaryl) alkanone O-phenyl oximes: versatile reagents for syntheses of quinazolines

F Portela-Cubillo, JS Scott, JC Walton - Chemical communications, 2008 - pubs.rsc.org
2-(Aminoaryl)alkanone O -phenyl oximes : versatile reagents for syntheses of quinazolines -
Chemical Communications (RSC Publishing) DOI:10.1039/B803630F Royal Society of …

Synthesis of aminocyclitols by intramolecular reductive coupling of carbohydrate derived δ-and ε-functionalized oxime ethers promoted by tributyltin hydride or …

J Marco-Contelles, P Gallego… - The Journal of …, 1997 - ACS Publications
The intramolecular reductive coupling of a series of simple or polyoxygenated oxime ethers
δ-or ε-functionalized with bromide, α, β-unsaturated ester, aldehyde, or ketone groups is …