Abnormal expression of Krüppel-like transcription factors and their potential values in lung cancer

Y Shi, M Yao, S Shen, L Wang, D Yao - Heliyon, 2024 - cell.com
Lung cancer still is one of the most common malignancy tumors in the world. However, the
mechanisms of its occurrence and development have not been fully elucidated. Zinc finger …

The Kruppel-like Factor (KLF) Family, Diseases, and Physiological Events

K Yuce, AI Ozkan - Gene, 2023 - Elsevier
Abstract The Kruppel-Like Factor family of regulatory proteins, which has 18 members, is
transcription factors. This family contains zinc finger proteins, regulates the activation and …

[HTML][HTML] Pan-cancer analysis of Krüppel-like factor 3 and its carcinogenesis in pancreatic cancer

J Zhu, H Teng, X Zhu, J Yuan, Q Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Krüppel-like factor 3 (KLF3) is a key transcriptional repressor, which is involved
in various biological functions such as lipogenesis, erythropoiesis, and B cell development …

[HTML][HTML] KLF3 promotes colorectal cancer growth by activating WNT1

W Shen, L Yuan, B Hao, J Xiang, F Cheng… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Objective: The function of Kruppel-like factor 3 (KLF3) remains largely unexplored in
colorectal cancer (CRC). Methods: KLF3 expression in CRC was assessed through qPCR …

Single-cell RNA sequencing and bulk sequencing reveal the immunosuppressive role of malignant cells in triple-negative breast cancer

R Hu, M Chen, X Fan, M Zhao, X Huang, J Zhang - Gene Reports, 2024 - Elsevier
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer and
the limiting efficacy is achieved for TNBC patients with immunotherapy. The role of …