Biotechnological advances in the synthesis of modified chondroitin towards novel biomedical applications

D Cimini, E Bedini, C Schiraldi - Biotechnology Advances, 2023 - Elsevier
Chondroitin sulfate (CS) is a well-known glycosaminoglycan present in a large variety of
animal tissues, with an outstanding structural heterogeneity mainly related to molecular …

[HTML][HTML] Heterologous production of chondroitin

MR Couto, JL Rodrigues, LR Rodrigues - Biotechnology Reports, 2022 - Elsevier
Chondroitin sulfate (CS) is a glycosaminoglycan with a broad range of applications being a
popular dietary supplement for osteoarthritis. Usually, CS is extracted from animal sources …

Bacterial glycobiotechnology: A biosynthetic route for the production of biopharmaceutical glycans

BS Paliya, VK Sharma, MG Tuohy, HB Singh… - Biotechnology …, 2023 - Elsevier
The recent advancement in the human glycome and progress in the development of an
inclusive network of glycosylation pathways allow the incorporation of suitable machinery for …

Production of different molecular weight glycosaminoglycans with microbial cell factories

D Wang, L Hu, R Xu, W Zhang, H Xiong, Y Wang… - Enzyme and Microbial …, 2023 - Elsevier
Glycosaminoglycans (GAGs) are naturally occurring acidic polysaccharides with wide
applications in pharmaceuticals, cosmetics, and health foods. The diverse biological …

Comparative analysis of antioxidant, anticholinesterase, and antibacterial activity of microbial chondroitin sulfate and commercial chondroitin sulfate

T Unver, AS Erenler, M Bingul… - Chemistry & …, 2023 - Wiley Online Library
Chondroitin synthesis was performed using the recombinant Escherichia coli (C2987) strain
created by transforming the plasmid pETM6‐PACF‐vgb, which carries the genes …

Development of microbial chondroitin sulfate-based proton exchange membranes for microbial fuel cells

SA Erenler, T Unver, BF Ozaslan, S Koytepe, S Sezer - Fuel, 2024 - Elsevier
Technological developments have led to a significant increase in energy demand, and thus
the interest in alternative energy has increased in the same direction. For this reason, fossil …

Biochemical effect evaluation of microbial chondroitin sulphate in experimental knee osteoarthritis model

A ERENLER, A Bay Karabulut… - Fresenius …, 2022 - avesis.inonu.edu.tr
Osteoarthritis (OA) is the most common chronic joint disease, primarily due to aging.
Chondroitin sulfate (CS) is a glycosaminoglycan (GAG) commonly used to treat …

Comparative evaluation of cytotoxic and anti-metastatic function of microbial chondroitin sulfate and animal-originated commercial chondroitin sulfate in cancer cells

T Unver, S Celik-Uzuner… - Cellular and Molecular …, 2023 - mail.cellmolbiol.org
Cancer has the second-highest mortality rate worldwide after cardiovascular disease. In
addition, breast and cervical cancer are two of the leading causes of cancer-related deaths …

[引用][C] Mikrobiyal kondroitin sülfatın antifungal etkisinin çeşitli Candida suşlarında farklı antimikrobiyal test yöntemleri kullanılarak karşılaştırılması

T ÜNVER - 2021