Unveiling the Significance of HLA and KIR Diversity in Underrepresented Populations

L Santiago-Lamelas, P Castro-Santos, Á Carracedo… - Biomedicines, 2024 - mdpi.com
Human leukocyte antigen (HLA) molecules and their relationships with natural killer (NK)
cells, specifically through their interaction with killer-cell immunoglobulin-like receptors …

Killer cell immunoglobulin-like receptor (KIR) genes and their HLA ligands in a Brazilian population

DM Cardozo, AV Marangon, F Guimarães… - Innate …, 2023 - journals.sagepub.com
Killer cell immunoglobulin-like receptors (KIR) exhibit extensive diversity, giving rise to
different KIR profiles in populations worldwide. This study aimed to investigate the …

Evaluation of the genetic diversity of KIR genes in patients with endometrial cancer

Z Shiravani, K Mirshekari, MH Larki, N Shafiee… - Journal of Reproductive …, 2024 - Elsevier
Endometrial cancer (EC) constitutes more than half of all genital cancers in women, with an
increasing incidence in different countries. Natural killer cells (NK cells) are kinds of innate …

KIR Genotypes Impact Progression to Hepatocellular Carcinoma in Patients with Chronic Hepatitis C Infection

W Abdelmaguid, D Maher, MAS Kohla, S Ezzat, I Moaz… - Livers, 2023 - mdpi.com
Simple Summary Egypt has the highest prevalence of hepatitis C infection in the world with
a dramatic increase in the incidence of hepatocellular carcinoma (HCC) observed during the …

陕西地区汉族人群KIR 基因多态性的研究

王天菊, 尚利侠, 徐华, 武君华, 陈乐, 王满妮, 王小芳… - 临床输血与检验, 2023 - lcsxyjy.com
目的研究陕西地区汉族人群自然杀伤细胞免疫球蛋白样受体(KIR) 基因多态性及基因型特点.
方法随机抽取474 名陕西地区造血干细胞无偿捐献者外周血, KIR 基因分型采用聚合酶链式反应 …

WHOLE EXOME SEQUENCING OF A PATIENT WITH MORBID OBESITY: TRIO ANALYSIS, PRELIMINARY RESULTS

N Sikhayeva, A Nakysh, T Utupov… - Eurasian Journal of …, 2023 - biotechlink.org
Morbid obesity is a severe form of obesity that leads to numerous cardiovascular, metabolic
diseases and cancers, as well as increased mortality. Whole-exome sequencing is the …

Polymorphism of Killer Cell Immunoglobulin-like Receptor Gene in Shaanxi Han Population

W Tian-ju, S Li-xia, XU Hua - JOURNAL OF CLINICAL TRANSFUSION AND … - lcsxyjy.com
Objective To analyze killer cell immunoglobulin-like receptor (KIR) gene polymorphism and
genotypes characteristics in Shaanxi Han population. Methods The peripheral blood of 474 …