RARγ-C-Fos-PPARγ2 signaling rather than ROS generation is critical for all-trans retinoic acid-inhibited adipocyte differentiation

X Wang, P Yang, J Liu, H Wu, W Yu, T Zhang, H Fu… - Biochimie, 2014 - Elsevier
Obesity has become a worldwide public health problem, which is mainly determined by
excess energy intake and adipose tissue expansion. Adipose tissue expansion can occur …

Organization of nuclear architecture during adipocyte differentiation

NL Charó, MI Rodríguez Ceschan, NM Galigniana… - Nucleus, 2016 - Taylor & Francis
Obesity is a serious health problem worldwide since it is a major risk factor for chronic
diseases such as type II diabetes. Obesity is the result of hyperplasia (associated with …

Chromatin remodeling and cardiac differentiation of stem cells

M Ullah, H Iqbal, K Haneef, I Khan, A Salim - Stem cells: from potential to …, 2021 - Springer
Cell fate commitment is achieved by cell type-specific transcription, which in turn is guided
by epigenetic mechanisms. Epigenetic and chromatin modifications play important roles in …

FOS Inhibits the Differentiation of Intramuscular Adipocytes in Goats

T Hu, Z Li, C Gong, Y Xiong, S Sun, J Xing, Y Li, R Li… - Genes, 2023 - mdpi.com
Goat intramuscular fat (IMF) deposition is precisely regulated by many key genes as well as
transcription factors. Nevertheless, the potential of the regulators of goat IMF deposition …

Transcriptome and Metabolome Analyses Provide Insight into the Glucose-Induced Adipogenesis in Porcine Adipocytes

S Jiang, G Zhang, J Miao, D Wu, X Li, J Li, J Lu… - Current Issues in …, 2024 - mdpi.com
Glucose is a major energy substrate for porcine adipocytes and also serves as a regulatory
signal for adipogenesis and lipid metabolism. In this study, we combined transcriptome and …

The PPARγ locus makes long-range chromatin interactions with selected tissue-specific gene loci during adipocyte differentiation in a protein kinase A dependent …

SE LeBlanc, Q Wu, AR Barutcu, H Xiao, Y Ohkawa… - PloS one, 2014 - journals.plos.org
Differentiation signaling results in reprogramming of cellular gene expression that leads to
morphological changes and functional specialization of a precursor cell. This global change …

Adipogenesis is under surveillance of Hsp90 and the high molecular weight Immunophilin FKBP51

J Toneatto, NL Charó, NM Galigniana… - Adipocyte, 2015 - Taylor & Francis
Adipose tissue plays a central role in the control of energy balance as well as in the
maintenance of metabolic homeostasis. It was not until recently that the first evidences of the …

[HTML][HTML] 山羊转录因子c-fos克隆,鉴定及功能分析

胡婷婷, 王永, 陈定双, 龚成思, 李艳艳, 熊燕… - 生物工程 …, 2023 - cjb.ijournals.cn
转录因子c-fos 在细胞增殖, 分化和肿瘤形成中发挥着重要作用. 本研究旨在获得山羊c-fos
基因序列并阐明其生物学性质, 进一步利用过表达手段揭示c-fos 在山羊皮下脂肪细胞分化过程 …

Methods for Treating and Preventing Cardiac Dysfunction in Septic Shock

IJ Goldberg, K Drosatos - US Patent App. 14/000,800, 2014 - Google Patents
Cardiac dysfunction during sepsis is due, at least in part, to cardiac energy deficiency. It has
been discovered that lipopolysaccharide (LPS)-mediated cardiac dysfunction is prevented …

[引用][C] 探究急性脑梗死患者血清PPARγ 检测的意义

孔杰辰, 李美玉, 赵颖宇, 徐辉, 柳明霞, 林黎娟 - 中国临床实用医学, 2016