Multiple sclerosis (MS) is a chronic autoimmune demyelinating and neurodegenerative
disease of the central nervous system with a wide variety of clinical phenotypes. In spite of …

MRI plays a central role in the diagnosis of multiple sclerosis (MS) and in the monitoring of
disease course and treatment response. Advanced MRI techniques have shed light on MS …

Background Easily accessible biomarkers enabling the identification of those patients with
multiple sclerosis (MS) who will accumulate irreversible disability in the long term are …

Background Enhanced prediction of progression in secondary progressive multiple sclerosis
(SPMS) could improve clinical trial design. Machine learning (ML) algorithms are methods …

Background: We conducted this study to estimated the time of conversion from relapsing-
remitting MS (RRMS) to SPMS and its early predictor factors. Methods: In this retrospective …

Cladribine is a purine nucleoside analog initially developed in the 1970s as a treatment for
various blood cancers. Due to the molecule's ability to preferentially reduce T and B …

Background Multiple sclerosis (MS) leads to demyelination and neurodegeneration with
autoimmune responses in central nervous system. Patients begin with a relapsing–remitting …

Background Atrophied T2 lesion volume at MRI is an imaging measure that reflects the
replacement of T2 lesions by cerebrospinal fluid spaces in patients with multiple sclerosis …

The course of multiple sclerosis begins with a relapsing-remitting phase, which evolves into
a secondarily progressive form over an extremely variable period, depending on many …

Multiple Sclerosis (MS) is a neurodegenerative autoimmune disorder of the central nervous
system (CNS) characterized by the recruitment of self-reactive T lymphocytes, mainly …