Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets
T Loganathan, GP Doss C - Functional & integrative genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …
the origin, course of action and treatment of any disease state is essential. A microscopic …
Computational tools and resources for CRISPR/Cas genome editing
The past decade has witnessed a rapid evolution in identifying more versatile clustered
regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) …
regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) …
Host-mediated gene engineering and microbiome-based technology optimization for sustainable agriculture and environment
The agricultural sector and environmental safety both work hand in hand to promote
sustainability in important issues like soil health, plant nutrition, food safety, and security …
sustainability in important issues like soil health, plant nutrition, food safety, and security …
An insight into modern targeted genome-editing technologies with a special focus on CRISPR/Cas9 and its applications
Genome-editing technology has enabled scientists to make changes in model organisms'
DNA at the genomic level to get biotechnologically important products from them. Most …
DNA at the genomic level to get biotechnologically important products from them. Most …
CRISPR/Cas-based modifications for therapeutic applications: a review
N Bharathkumar, A Sunil, P Meera, S Aksah… - Molecular …, 2022 - Springer
The CRISPR–Cas genome editing system is an intrinsic property of a bacteria-based
immune system. This employs a guide RNA to detect and cleave the PAM-associated target …
immune system. This employs a guide RNA to detect and cleave the PAM-associated target …
A review on CRISPR/Cas-based epigenetic regulation in plants
Epigenetic changes are the heritable modifications in genes without altering DNA
sequences. The epigenetic changes occur in the plant genomes to regulate gene …
sequences. The epigenetic changes occur in the plant genomes to regulate gene …
Engineering plants using diverse CRISPR-associated proteins and deregulation of genome-edited crops
The CRISPR/Cas system comprises RNA-guided nucleases, the target specificity of which is
directed by Watson–Crick base pairing of target loci with single guide (sg) RNA to induce the …
directed by Watson–Crick base pairing of target loci with single guide (sg) RNA to induce the …
[HTML][HTML] Clinical applications of the CRISPR/Cas9 genome-editing system: Delivery options and challenges in precision medicine
M Khoshandam, H Soltaninejad, M Mousazadeh… - Genes & …, 2024 - Elsevier
CRISPR/Cas9 is an effective gene editing tool with broad applications for the prevention or
treatment of numerous diseases. It depends on CRISPR (clustered regularly interspaced …
treatment of numerous diseases. It depends on CRISPR (clustered regularly interspaced …
A review on CRISPR/Cas: a versatile tool for cancer screening, diagnosis, and clinic treatment
X Yang, B Zhang - Functional & Integrative Genomics, 2023 - Springer
Cancer is one of the leading causes of death worldwide and it has the trend of increase
incidence. However, in the past decades, as quickly developed new technologies and …
incidence. However, in the past decades, as quickly developed new technologies and …
Engineering abiotic stress tolerance in crop plants through CRISPR genome editing
Environmental abiotic stresses challenge food security by depressing crop yields often
exceeding 50% of their annual production. Different methods, including conventional as well …
exceeding 50% of their annual production. Different methods, including conventional as well …