Although the human lifespan has increased in the past century owing to advances in
medicine and lifestyle, the human healthspan has not kept up the same pace, especially in …

Discovering why some people's cognitive abilities decline more than others is a key
challenge for cognitive ageing research. The most effective strategy may be to address …

Growing evidence supports the use of plasma levels of tau phosphorylated at threonine 181,
amyloid-β, neurofilament light and glial fibrillary acidic protein as promising biomarkers for …

Brain age is a neuroimaging-based biomarker of aging. This study examined whether the
difference between brain age and chronological age (brain-PAD) is associated with …

Children's cognitive functioning and educational performance are socially stratified. Social
inequality, including classism and racism, may operate partly via epigenetic mechanisms …

Obesity and sarcopenia are associated with cognitive impairments at older age. Current
research suggests that blood biomarkers may mediate this body-brain crosstalk, altering …

Background Individuals who are socioeconomically disadvantaged are at increased risk for
aging-related diseases and perform less well on tests of cognitive function. The weathering …

Cognitive abilities are compromised with advancing age posing a great risk for the
development of dementia and other related brain disorders. Genetic susceptibility as well as …

Mechanisms of resilience against tau pathology in individuals across the Alzheimer's
disease spectrum are insufficiently understood. Longitudinal data are necessary to reveal …

Although the notion of cognitive aging is commonly associated with decline in popular
culture, a wealth of scientific literature shows that cognitive aging is more aptly characterized …