Diagnostic and therapeutic potential of circulating-free DNA and cell-free RNA in cancer management

S Hassan, A Shehzad, SA Khan, W Miran, S Khan… - Biomedicines, 2022 - mdpi.com
Over time, molecular biology and genomics techniques have been developed to speed up
the early diagnosis and clinical management of cancer. These therapies are often most …

Potential impact of PI3K-AKT signaling pathway genes, KLF-14, MDM4, miRNAs 27a, miRNA-196a genetic alterations in the predisposition and progression of breast …

OR Alzahrani, R Mir, HE Alatwi, YM Hawsawi… - Cancers, 2023 - mdpi.com
Simple Summary The genomic landscape of breast cancer (BC) is complex. Previous
research studies have not extensively elucidated the correlation of genotypes and allele …

PRKCE non-coding variants influence on transcription as well as translation of its gene

K Khan, S Zafar, A Hafeez, Y Badshah, K Shahid… - RNA biology, 2022 - Taylor & Francis
Untranslated regions of the gene play a crucial role in gene expression regulation at mRNA
and protein levels. Mutations at UTRs impact expression by altering transcription factor …

KLF14 activates the JNK-signaling pathway to induce S-phase arrest in cervical cancer cells

Y Du, H Ye, M Lin, L Cao - Frontiers in Immunology, 2023 - frontiersin.org
Objective To explore the role of Krüppel-like factor 14 (KLF14) and its underlying
mechanism (s) of action in cell-cycle regulation in cervical cancer. Methods Lentiviral …

Cross talk of tumor protein D52 (TPD52) with KLF9, PKCε, and MicroRNA 223 in ovarian cancer

K Khan, S Zafar, Y Badshah, NM Ashraf… - Journal of Ovarian …, 2023 - Springer
Background Gynecologic cancers comprise malignancies in the female reproductive organs.
Ovarian cancer ranks sixth in terms of incidence rates while seventh in terms of mortality …

Kruppel 样因子14 介导的JAK-STAT 信号通路对非小细胞肺癌预后的影响.

王鹏, 姚苏梅, 吕学东, 陈金亮 - Journal of Practical …, 2024 - search.ebscohost.com
目的探讨Kruppel 样因子14 (KLF14) 介导的Janus 激酶-信号转导子与转录激活子(JAKSTAT)
信号通路对非小细胞肺癌(NSCLC) 预后的影响. 方法收集2018 年1 月至2019 年9 …

[PDF][PDF] Diagnostic and Therapeutic Potential of Circulating-Free DNA and Cell-Free RNA in Cancer Management. Biomedicines 2022, 10, 2047

S Hassan, A Shehzad, SA Khan, W Miran, S Khan… - 2022 - academia.edu
Over time, molecular biology and genomics techniques have been developed to speed up
the early diagnosis and clinical management of cancer. These therapies are often most …

miR-124 as a Liquid Biopsy Prognostic Biomarker in Small Extracellular Vesicles from NSCLC Patients

D Sanchez-Cabrero, Á Garcia-Guede… - International Journal of …, 2023 - mdpi.com
Despite advances in non-small cell lung cancer (NSCLC) research, this is still the most
common cancer type that has been diagnosed up to date. microRNAs have emerged as …