In a pivotal trial (EPIC-HR), a 5-day course of oral ritonavir-boosted nirmatrelvir, given early
during symptomatic SARS-CoV-2 infection (within three days of symptoms onset) …

We use viral kinetic models fitted to viral load data from in vitro studies to explain why the
SARS-CoV-2 Omicron variant replicates faster than the Delta variant in nasal cells, but …

In the UK, the 2022 monkeypox outbreak was heralded by an imported case on May 7,
2022, with a typical history and presentation for imported monkeypox, including a …

A thorough understanding of the inhalation dynamics of infectious aerosols indoors and
infection dynamics within the host by inhaled viruses such as severe acute respiratory …

Within‐host model specified by viral dynamic parameters is a mainstream tool to understand
SARS‐CoV‐2 replication cycle in infected patients. The parameter uncertainty further affects …

Hepatitis B virus (HBV) is a global health threat, and its elimination by 2030 has been
prioritised by the World Health Organisation. Here we present an age-structured model for …

The role of antiviral treatment in coronavirus disease 2019 hospitalized patients is
controversial. To address this question, we analyzed simultaneously nasopharyngeal viral …

The ongoing global pandemic of COVID-19 poses unprecedented public health risks for
governments and societies around the world, which have been exacerbated by the …

The SARS-CoV-2 virus disproportionately causes serious illness and death in older
individuals. In order to have the greatest impact in decreasing the human toll caused by the …

Mathematical models are a core component in the foundation of cancer theory and have
been developed as clinical tools in precision medicine. Modeling studies for clinical …