Milk-derived extracellular vesicles in inter-organism, cross-species communication and drug delivery

R Sanwlani, P Fonseka, SV Chitti, S Mathivanan - Proteomes, 2020 - mdpi.com
Milk is considered as more than a source of nutrition for infants and is a vector involved in
the transfer of bioactive compounds and cells. Milk contains abundant quantities of …

Mesenchymal stem cell derived extracellular vesicles in aging

J Boulestreau, M Maumus, P Rozier… - Frontiers in cell and …, 2020 - frontiersin.org
Aging is associated with high prevalence of chronic degenerative diseases that take a large
part of the increasing burden of morbidities in a growing demographic of elderly people …

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles

U Erdbrügger, CJ Blijdorp, IV Bijnsdorp… - Journal of …, 2021 - Wiley Online Library
Urine is commonly used for clinical diagnosis and biomedical research. The discovery of
extracellular vesicles (EV) in urine opened a new fast‐growing scientific field. In the last …

Comparing approaches to normalize, quantify, and characterize urinary extracellular vesicles

CJ Blijdorp, OAZ Tutakhel, TA Hartjes… - Journal of the …, 2021 - journals.lww.com
Background Urinary extracellular vesicles (uEVs) are a promising source for biomarker
discovery, but optimal approaches for normalization, quantification, and characterization in …

Nephron mass determines the excretion rate of urinary extracellular vesicles

CJ Blijdorp, TA Hartjes, KY Wei… - Journal of …, 2022 - Wiley Online Library
Urinary extracellular vesicles (uEVs) are emerging as non‐invasive biomarkers for various
kidney diseases, but it is unknown how differences in nephron mass impact uEV excretion …

Factors mediating exercise‐induced organ crosstalk

R Sabaratnam, JFP Wojtaszewski… - Acta …, 2022 - Wiley Online Library
Exercise activates a plethora of metabolic and signalling pathways in skeletal muscle and
other organs causing numerous systemic beneficial metabolic effects. Thus, regular exercise …

Extracellular vesicles as mediators of cellular crosstalk between immune system and kidney graft

M Quaglia, S Dellepiane, G Guglielmetti… - Frontiers in …, 2020 - frontiersin.org
Extracellular vesicles (EVs) are known immune-modulators exerting a critical role in kidney
transplantation (KT). EV bioactive cargo includes graft antigens, costimulatory/inhibitory …

Urinary extracellular vesicles: Assessment of pre‐analytical variables and development of a quality control with focus on transcriptomic biomarker research

K Barreiro, OP Dwivedi, S Valkonen… - Journal of …, 2021 - Wiley Online Library
Urinary extracellular vesicles (uEV) are a topical source of non‐invasive biomarkers for
health and diseases of the urogenital system. However, several challenges have become …

Comparison of urinary extracellular vesicle isolation methods for transcriptomic biomarker research in diabetic kidney disease

K Barreiro, OP Dwivedi, G Leparc… - Journal of …, 2020 - Wiley Online Library
Abstract Urinary Extracellular Vesicles (uEV) have emerged as a source for biomarkers of
kidney damage, holding potential to replace the conventional invasive techniques including …

Exosomes: emerging therapy delivery tools and biomarkers for kidney diseases

C Jin, P Wu, L Li, W Xu, H Qian - Stem cells international, 2021 - Wiley Online Library
Exosomes are nanometer‐sized small EVs coated with bilayer structure, which are released
by prokaryotic and eukaryotic cells. Exosomes are rich in a variety of biologically active …