Impact of the diseased lung microenvironment on the in vivo fate of inhaled particles

J Gai, L Liu, X Zhang, J Guan, S Mao - Drug Discovery Today, 2024 - Elsevier
Inhalation drug delivery is superior for local lung disease therapy. However, there are
several unique absorption barriers for inhaled drugs to overcome, including limited drug …

Molecular Mechanisms Responsible for the Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Lung Fibrosis

CR Harrell, V Djonov, A Volarevic… - International journal of …, 2024 - mdpi.com
Mesenchymal stem cell-derived exosomes (MSC-Exos) are nano-sized extracellular
vesicles which contain various MSC-sourced anti-fibrotic, immunoregulatory and angio …

Advances in the study of silica nanoparticles in lung diseases

LH Ao, YG Wei, HR Tian, H Zhao, J Li… - Science of The Total …, 2023 - Elsevier
Silicon dioxide nanoparticles (SiNPs) are one of the major forms of silicon dioxide and are
composed of the most-abundant compounds on earth. Based on their excellent properties …

Ischemia-Modified Albumin (IMA) Is Associated with Poor Survival in Patients with Newly Diagnosed Idiopathic Pulmonary Fibrosis (IPF): A Pilot Study

A Zinellu, S Zoroddu, S Fois, S Mellino, C Scala… - Antioxidants, 2024 - mdpi.com
There are increasing efforts to better predict adverse outcomes for idiopathic pulmonary
fibrosis (IPF). Our aim was to assess the prognostic potential of ischemia-modified albumin …

Respiratory Diseases Associated With Organic Dust Exposure

JA Poole, JL Zamora-Sifuentes… - The Journal of Allergy …, 2024 - Elsevier
Organic dusts are complex bioaerosol mixtures comprised of dust and par ticulate matter of
organic origin. These include components from bacteria, fungi, pollen, and viruses to …

Ferroptosis Mediates Pulmonary Fibrosis: Implications for the Effect of Astragalus and Panax notoginseng Decoction

J Wen, C Wang, L Song, Y Wang… - Canadian …, 2024 - Wiley Online Library
Context. Ferroptosis is known to influence the pathogenesis of pulmonary fibrosis.
Astragalus and Panax notoginseng are used to treat pulmonary fibrosis; however, the …

Imbalance of dendritic cell function in pulmonary fibrosis

Y Yuan - Cytokine, 2024 - Elsevier
Pulmonary fibrosis (PF) is a chronic, irreversible interstitial lung disease. The pathogenesis
of PF remains unclear, and there are currently no effective treatments or drugs that can …

Integrated multiomic analysis identifies TRIP13 as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis

L St. Pierre, A Berhan, EK Sung, JR Alvarez, H Wang… - bioRxiv, 2024 - biorxiv.org
Idiopathic pulmonary fibrosis (IPF) is a lethal progressive lung disease urgently needing
new therapies. Current treatments only delay disease progression, leaving lung transplant …

[图书][B] Fibrotic lung disease: early signs, treatment and outcomes

I Belo - 2024 - openarchive.ki.se
Idiopathic pulmonary fibrosis (IPF) has gained a lot of attention by the research community in
recent decades. Thanks to enhanced understanding on pathophysiological mechanisms …