Poly (ADP ribose) polymerase (PARP) inhibitors are novel targeted anticancer agents that
have been widely used in patients with cancer, particularly in patients with breast‑related …

Transmembrane drug transporters can be important determinants of the pharmacokinetics,
efficacy, and safety profiles of drugs. To investigate the potential cooperative and/or …

The isolated perfused rat liver (IPRL) model provides a mechanistic understanding of the
organic-anion-transporting polypeptide (OATP/Oatp)-mediated pharmacokinetics in the …

HepaRG cells are highly‐differentiated human hepatoma cells, which are increasingly
recognized as a convenient cellular model for in vitro evaluation of hepatic metabolism …

Drug-induced liver injury (DILI) is a critical concern in modern medicine, encompassing a
broad spectrum of liver-related abnormalities caused by various pharmaceutical …