Background Optimal CPAP strategy to prevent CPAP failure defined as need for
endotracheal intubation is unknown. Objective To evaluate the risk of CPAP failure in infants …

The most recent Neonatal Resuscitation Programme (NRP 5th edition) guidelines recognise
the T-piece resuscitator (Neopuff®) device as an acceptable method of administering a pre …

Animal models have made and continue to make important contributions to neonatal
medicine. For example, studies in fetal sheep have taught us much about the physiology of …

Background CPAP is a technique of respiratory support generating a continuous distending
pressure applied to the lung and delivered to spontaneously breathing infants with …

Neonatologists treating extremely premature infants in the delivery room are faced with
many dilemmas, not least how best to support their breathing. A balance must be struck …

In term and preterm infants, the transition from intrauterine to extrauterine life requires the
lungs to change from being fluid-filled to air-filled and for regular spontaneous respiration to …

Stabilisation and resuscitation of babies at birth is one of the most frequently performed
procedures and requires considerable skill. If it is not done well, the baby may suffer …

Introduction International resuscitation guidelines suggest to use positive end-expiratory
pressure (PEEP) during manual ventilation of neonates. Aim of our study was to test the …

Background: We investigated the effects of positive end-expiratory pressure (PEEP) and
tidal volume (VT) on lung aeration, pulmonary mechanics, and the distribution of ventilation …

BACKGROUND: Ventilator injury has been implicated in the pathogenesis of
bronchopulmonary dysplasia. Avoiding invasive ventilation could reduce lung injury, and …