Intrapericardial drug delivery is a promising procedure, with the ability to localize
therapeutics with the heart. Gelfoam particles are nontoxic, inexpensive, nonimmunogenic …

After cardiovascular injury, numerous pathological processes adversely impact the
homeostatic function of cardiomyocyte, macrophage, fibroblast, endothelial cell, and …

1814 have been implanted into the ischemic brain. 11 Studies have described a
complement of ionic currents in both the undifferentiated and differentiated MSC, 12, 13 …

Ischemic heart disease is the main cause of death and morbidity in most industrialized
countries. Stem-and progenitor cell-based treatment approaches for ischemic heart disease …

This work aimed to evaluate cardiac morphology/function and histological changes induced
by bone marrow cells (BMCs) and cultured mesenchymal stem cells (MSCs) injected at the …

Decellularized porcine myocardium has shown many benefits as a cell delivery scaffold for
cardiac therapy. However, using full thickness decellularized myocardium as cardiac patch …

Over the past decade, cell therapy has emerged as a potential new treatment of a variety of
cardiac diseases, including acute myocardial infarction, refractory angina, and chronic heart …

Background Cell death due to anoikis, necrosis and cell egress from transplantation sites
limits functional benefits of cellular cardiomyoplasty. Cell dissociation and suspension …

Abstract Introduction Mesenchymal stem cells (MSCs) have been associated with reduced
arrhythmias; however, the mechanism of this action is unknown. In addition, limited retention …

Single-vessel, intracoronary infusion of stem cells under stop-flow conditions has proven
safe but achieves only limited myocardial coverage. Continuous flow intracoronary delivery …