Schizophrenia is a severe complex mental disorder affecting 0.5–1% of the world
population. To date, diagnosis of the disease is mainly based on personal and thus …

Increased risk for autism spectrum disorders (ASD) is attributed to hundreds of genetic loci.
The convergence of ASD variants have been investigated using various approaches …

MicroRNAs (miRNAs) are small non-coding RNAs that act as potent regulators of gene
expression. A recent GWAS reported the rs1625579 SNP, located downstream of miR-137 …

Genetic generalized epilepsies (GGEs) have a lifetime prevalence of 0.3% and account for
20–30% of all epilepsies. Despite their high heritability of 80%, the genetic factors …

BackgroundGroup-level results suggest that relative to healthy controls (HCs), ultra-high-risk
(UHR) and first-episode psychosis (FEP) subjects show alterations in neuroanatomy …

The TCF4 gene is the subject of numerous and varied investigations of it's role in the
genesis of neuropsychiatric disease. The gene has been identified as the cause of Pitt …

Autism spectrum disorder is a heterogeneous neurodevelopmental disorder with strong
genetic basis. To identify common genetic variations conferring the risk of ASD, we …

The powerful genome-wide association studies (GWAS) revealed common mutations that
increase susceptibility for schizophrenia (SZ) and bipolar disorder (BD), but the vast majority …

Applying tissue-specific deconvolution of transcriptional networks to identify their master
regulators (MRs) in neuropsychiatric disorders has been largely unexplored. Here, using …

Identifying the genetic underpinnings of complex diseases offers insight into the etiological
mechanisms leading to manifestation of the disease. New and more effective treatments for …