Insecticide resistance in insects severely threatens both human health and agriculture,
making insecticides less compelling and valuable, leading to frequent pest management …

Highlights•ABCC2-and ABCC3-based Cry1 resistance was extended to several Lepidoptera
species.•ABCG modulates cuticle thickness in Culex pipiens and contributes to deltamethrin …

Ongoing host–pathogen interactions can trigger a coevolutionary arms race, while genetic
diversity within the host can facilitate its adaptation to pathogens. Here, we used the …

Lambda-cyhalothrin is one of the most important pyrethroids used for controlling wheat
aphids. Extensive spraying of lambda-cyhalothrin has led to the development of high …

Bioinsecticides and transgenic crops based on the bacterial pathogen Bacillus thuringiensis
(Bt) can effectively control diverse agricultural insect pests, nevertheless, the evolution of …

Clarifying the molecular mechanisms of cotton aphid resistance to various insecticides is
crucial for the long-term safe application of insecticides in chemical control. ATP-binding …

Helicoverpa armigera is a worldwide pest that has been efficiently controlled by transgenic
plants expressing Bt Cry toxins. To exert toxicity, Cry toxins bind to different receptors …

Phytochemicals are a class of potential pesticides for pest control. Our previous studies have
demonstrated that the development of Spodoptera litura is suppressed by two …

Pore-forming toxins (PFTs) are effective tools for pathogens infection. By disrupting epithelial
barriers and killing immune cells, PFTs promotes the colonization and reproduction of …

Trade-offs between evolutionary gain and loss are prevalent in nature, yet their genetic
basis is not well resolved. The evolution of insect resistance to insecticide is often …