Astrocytes as key regulators of brain energy metabolism: new therapeutic perspectives

E Beard, S Lengacher, S Dias, PJ Magistretti… - Frontiers in …, 2022 - frontiersin.org
Astrocytes play key roles in the regulation of brain energy metabolism, which has a major
impact on brain functions, including memory, neuroprotection, resistance to oxidative stress …

The neuroscience of drug reward and addiction

ND Volkow, M Michaelides, R Baler - Physiological reviews, 2019 - journals.physiology.org
Drug consumption is driven by a drug's pharmacological effects, which are experienced as
rewarding, and is influenced by genetic, developmental, and psychosocial factors that …

Brain metabolism in health, aging, and neurodegeneration

S Camandola, MP Mattson - The EMBO journal, 2017 - embopress.org
Brain cells normally respond adaptively to bioenergetic challenges resulting from ongoing
activity in neuronal circuits, and from environmental energetic stressors such as food …

A synopsis on aging—Theories, mechanisms and future prospects

JP da Costa, R Vitorino, GM Silva, C Vogel… - Ageing research …, 2016 - Elsevier
Answering the question as to why we age is tantamount to answering the question of what is
life itself. There are countless theories as to why and how we age, but, until recently, the very …

Clinical ascertainment of health outcomes among adults treated for childhood cancer

MM Hudson, KK Ness, JG Gurney, DA Mulrooney… - Jama, 2013 - jamanetwork.com
Importance Adult survivors of childhood cancer are known to be at risk for treatment-related
adverse health outcomes. A large population of survivors has not been evaluated using a …

Physical exercise and cognitive performance in the elderly: current perspectives

NJ Kirk-Sanchez, EL McGough - Clinical interventions in aging, 2014 - Taylor & Francis
In an aging population with increasing incidence of dementia and cognitive impairment,
strategies are needed to slow age-related decline and reduce disease-related cognitive …

Episodic memory in normal aging and Alzheimer disease: Insights from imaging and behavioral studies

D Tromp, A Dufour, S Lithfous, T Pebayle… - Ageing research …, 2015 - Elsevier
Age-related cognitive changes often include difficulties in retrieving memories, particularly
those that rely on personal experiences within their temporal and spatial contexts (ie …

[HTML][HTML] Promoting successful cognitive aging: a ten-year update

TJ Krivanek, SA Gale, BM McFeeley… - Journal of …, 2021 - content.iospress.com
A decade has passed since we published a comprehensive review in this journal
addressing the topic of promoting successful cognitive aging, making this a good time to …

Obesity and cognitive decline: role of inflammation and vascular changes

JCD Nguyen, AS Killcross, TA Jenkins - Frontiers in neuroscience, 2014 - frontiersin.org
The incidence of obesity in middle age is increasing markedly, and in parallel the
prevalence of metabolic disorders including cardiovascular disease and type II diabetes is …

Cognitive interventions in healthy older adults and people with mild cognitive impairment: a systematic review

J Reijnders, C van Heugten, M van Boxtel - Ageing research reviews, 2013 - Elsevier
Given that the research area of cognitive intervention studies in the aging population is
growing rapidly, it is important to review and gauge more recent intervention studies, in …