Impact of adenoviral stool load on adenoviremia in pediatric hematopoietic stem cell transplant recipients

A Srinivasan, C Klepper, A Sunkara… - The Pediatric …, 2015 - journals.lww.com
Background: Adenoviremia adversely affects prognosis in the post-hematopoietic stem cell
transplant setting. Methods: We sought to determine retrospectively the cutoff load of …

Valganciclovir inhibits human adenovirus replication and pathology in permissive immunosuppressed female and male Syrian hamsters

K Toth, B Ying, AE Tollefson, JF Spencer… - Viruses, 2015 - mdpi.com
Adenovirus infections of immunocompromised pediatric hematopoietic stem cell transplant
patients can develop into serious and often deadly multi-organ disease. There are no drugs …

Approach to infection and disease due to adenoviruses in solid organ transplantation

DF Florescu, EJ Stohs - Current Opinion in Infectious Diseases, 2019 - journals.lww.com
Distinguishing between adenovirus infection and disease is an important aspect in
adenovirus management as treatment is warranted only in symptomatic solid organ …

Adenoviral nephritis in a renal transplant recipient: case report and literature review

M Veer, R Abdulmassih, J Como, Z Min… - Transplant Infectious …, 2017 - Wiley Online Library
Adenovirus (AdV) infections in transplant recipients may cause invasive disease. We
present a case of granulomatous interstitial nephritis secondary to AdV infection in a renal …

Human adenovirus, polyomavirus, and parvovirus infections in patients undergoing hematopoietic stem cell transplantation

HH Hirsch, SA Pergam - Thomas' Hematopoietic Cell …, 2015 - Wiley Online Library
Summary Human adenovirus (HAdV), polyomavirus (HPyV), and parvovirus B19 (HPVB19)
infections can complicate hematopoietic stem‐cell transplantation by causing partly …

Update in the treatment of non-influenza respiratory virus infection in solid organ transplant recipients

SA Grim, GE Reid, NM Clark - Expert Opinion on Pharmacotherapy, 2017 - Taylor & Francis
Introduction: Despite the improved outcomes in solid organ transplantation with regard to
prevention of rejection and increased patient and graft survival, infection remains a common …

Oral USC-093, a novel homoserinamide analogue of the tyrosinamide (S)-HPMPA prodrug USC-087 has decreased nephrotoxicity while maintaining antiviral efficacy …

AE Tollefson, SB Riemann, B Ying, JF Spencer… - Antiviral Research, 2024 - Elsevier
Adenovirus infections of immunocompromised humans are a significant source of morbidity
and mortality. Presently, there is no drug specifically approved for the treatment of …

Severe necrotizing adenovirus tubulointerstitial nephritis in a kidney transplant recipient

R Parasuraman, PL Zhang… - Case Reports in …, 2013 - Wiley Online Library
Adenoviruses (AdV) are emerging pathogens with a prevalence of 11% viruria and 6.5%
viremia in kidney transplant recipients. Although AdV infection is common, interstitial …

Histologic Manifestations of Gastrointestinal Adenovirus Infection After Stem Cell Transplant

E Hissong, K Arora, C Andy, J Jessurun… - The American Journal …, 2024 - journals.lww.com
Adenovirus can cause severe disease in hematopoietic stem cell transplant (HSCT)
patients. Histopathologic features of this infection in gastrointestinal biopsies and their …

Efficacy of brincidofovir in pediatric stem cell transplant recipients with adenovirus infections

K Ehlert, JH Schulte, JS Kühl, P Lang… - Journal of the …, 2021 - academic.oup.com
Abstract Background Adenovirus (AdV) infections are of particular concern in pediatric
hematopoietic stem cell transplantation (HSCT) recipients as therapeutic options are limited …