Efficacy of brincidofovir in pediatric stem cell transplant recipients with adenovirus infections

K Ehlert, JH Schulte, JS Kühl, P Lang… - Journal of the …, 2021 - academic.oup.com
Abstract Background Adenovirus (AdV) infections are of particular concern in pediatric
hematopoietic stem cell transplantation (HSCT) recipients as therapeutic options are limited …

Biological antivirals for treatment of adenovirus infections

K Schaar, C Röger, T Pozzuto, J Kurreck… - Antiviral …, 2016 - journals.sagepub.com
Adenovirus (Ad) infections are usually mild and self-limiting, but severe systemic infections
and fatal diseases can occur, especially in immunosuppressed patients. Anti-adenoviral …

Fatal adenovirus encephalomyeloradiculitis in an umbilical cord stem cell transplant recipient

OO Awosika, JL Lyons, P Ciarlini, RE Phillips… - Neurology, 2013 - AAN Enterprises
Adenovirus infections frequently complicate allogeneic stem cell transplants, but nervous
system involvement, usually presenting as encephalitis, is atypical. Progression from …

Fulminant adenovirus hepatitis after hematopoietic stem cell transplant: Retrospective real-time PCR analysis for adenovirus DNA in two cases

N Kawashima, H Muramatsu, Y Okuno, Y Torii… - Journal of Infection and …, 2015 - Elsevier
Background Viral infection is one of the major causes of mortality in patients undergoing
hematopoietic stem cell transplant (HSCT). Systemic infection of adenovirus (AdV) has …

Disseminated adenovirus infection in cancer patients presenting with focal pulmonary consolidation

YJ Lee, P Palomino-Guilen, NE Babady… - Journal of clinical …, 2014 - Am Soc Microbiol
We report disseminated adenovirus (ADV) infection in four adult cancer patients presenting
with focal pulmonary consolidation. In all cases, ADV was recovered from respiratory …

Overview of the 3rd isirv‐Antiviral Group Conference–advances in clinical management

AC Hurt, DS Hui, A Hay… - Influenza and other …, 2015 - Wiley Online Library
This review highlights the main points which emerged from the presentations and
discussions at the 3rd isirv‐A ntiviral G roup C onference‐advances in clinical management …

Adenovirus infections in heart transplantation

DF Florescu, JY Kwon, I Dumitru - Cardiology in review, 2013 - journals.lww.com
Adenovirus infections have been associated with significant morbidity and mortality in
immunocompromised hosts. The clinical significance of adenovirus disease in heart …

Prodrug strategies for improved efficacy of nucleoside antiviral inhibitors

SJ Hurwitz, RF Schinazi - Current opinion in HIV and AIDS, 2013 - journals.lww.com
Prodrug strategies can address the issues of poor oral bioavailability and delivery of active
metabolites to the targeted cells. Additionally, NAPs demonstrate potential for improving …

Community-acquired respiratory viral infections in lung transplant recipients

S Shalhoub, S Husain - Current opinion in infectious diseases, 2013 - journals.lww.com
With current advanced investigating tools, the full impact of CARV infections in LTR is
increasingly coming to realization. Research for novel effective treatments and improved …

Use of unapproved or off-label drugs in Japan for the treatment of graft-versus-host disease and post-transplant viral infection

Y Kuwatsuka, Y Atsuta, A Hirakawa, N Uchida… - International Journal of …, 2020 - Springer
Many drugs are used for unapproved indications in Japan for post hematopoietic stem cell
transplant (HCT) complications. To investigate unapproved or off-label drug usage for graft …