Malaria and schistosomiasis are two major parasitic diseases that remain leading causes of
morbidity and mortality worldwide. Co-infections of these two parasites are common in the …

Simple Summary Tumor cells from the same specimen are functionally heterogeneous.
Cancer stem cells (CSCs) are populations of tumor cells with self-renewal and differentiation …

The adjuvant AS01 plays a key role in the immunogenicity of several approved human
vaccines with demonstrated high efficacy. Its adjuvant effect relies on activation of the innate …

Schistosomiasis is a neglected tropical disease caused by the helminth Schistosoma spp.
and has the second highest global impact of all parasites. Schistosoma are transmitted …

The key role of cancer stem cells (CSCs) in tumor development and therapy resistance
makes them essential biomarkers and therapeutic targets. Numerous agents targeting …

Information on the dynamics and decline/persistence of antibody titres is important in
vaccine development. A recent vaccine trial in malaria-exposed, healthy African adults and …

Parasites and microorganisms (protozoa, bacteria, and viruses) are still a concern despite
progress in hygiene and anti-infectious therapy. Humans are continuously exposed to these …

Malaria, caused by Plasmodium falciparum, remains a pressing global health concern.
Advancements in combating this parasite involve the development of a protein vaccine. This …

Background: Adjuvants may enhance the efficacy of vaccines. however, the efficacy of
adjuvant-associated COVID-19 vaccines (ACVs) remains unclear since the emergence of …

Cancer stem cells (CSCs) constitute a minority cell population characterized by unbounded
proliferative potential in both solid and hematological cancers. Despite sharing key stem cell …