New horizons in testosterone and the ageing male

T Ahern, FCW Wu - Age and Ageing, 2015 - academic.oup.com
The fall in testosterone levels with age appears to be a real phenomenon. Declining
testicular function and hypothalamic dysregulation appear to be the mechanisms explaining …

Late-onset hypogonadism: beyond testosterone

C Foresta, AE Calogero, F Lombardo… - Asian Journal of …, 2015 - journals.lww.com
Late-onset hypogonadism is defined as a combination of low testosterone (T) levels and
typical symptoms and signs. A major area of uncertainty is whether T concentrations are …

Sex hormone-binding globulin, androgens and mortality: the KORA-F4 cohort study

F Schederecker, A Cecil, C Prehn, J Nano… - Endocrine …, 2020 - ec.bioscientifica.com
Objective Sex hormone-binding globulin (SHBG) and androgens have been associated with
mortality in women and men, but controversy still exists. Our objective was to investigate …

The impact of long-term Testosterone Therapy (TTh) in renal function (RF) among hypogonadal men: An observational cohort study

M Alwani, RM Al-Zoubi, A Al-Qudimat… - Annals of Medicine …, 2021 - journals.lww.com
Objectives: Testosterone therapy (TTh) is the main treatment for elderly men with
hypogonadism. No evidence of the long-term effectiveness of TTh on renal function is …

Roles of testosterone replacement in cardiac ischemia–reperfusion injury

W Pongkan, SC Chattipakorn… - Journal of …, 2016 - journals.sagepub.com
Testosterone is an anabolic steroid hormone, which is the major circulating androgen
hormone in males. Testosterone levels decreasing below the normal physiological levels …

Androgen-regulated cardiac metabolism in aging men

G Barrientos, P Llanos, C Basualto-Alarcón… - Frontiers in …, 2020 - frontiersin.org
The prevalence of cardiovascular mortality is higher in men than in age-matched
premenopausal women. Gender differences are linked to circulating sex-related steroid …

[HTML][HTML] Low total testosterone levels are associated with the metabolic syndrome in elderly men: the role of body weight, lipids, insulin resistance, and inflammation; …

C Chrysohoou, D Panagiotakos… - The review of diabetic …, 2013 - ncbi.nlm.nih.gov
BACKGROUND: The prevalence of the metabolic syndrome (MetS) increases with age.
Among other changes, testosterone levels decline with age. The relationship between …

Association between sex hormone-binding globulin, atherogenic indices of plasma among young sedentary males

A Mohammadrezaei… - Nutrition and …, 2023 - journals.sagepub.com
Background: Males are more likely than females to suffer from cardiovascular disease
(CVD). So, sex hormones may modify these variations and affect the lipid profile. We …

Controversies in testosterone replacement therapy: testosterone and cardiovascular disease

K Hwang, M Miner - Asian journal of andrology, 2015 - journals.lww.com
The role of testosterone in the cardiovascular (CV) health of men is controversial. Data
suggest that both the condition and treatment of clinical hypogonadism is associated with …

Relationship of testis size and LH levels with incidence of major adverse cardiovascular events in older men with sexual dysfunction

G Rastrelli, G Corona, F Lotti, V Boddi… - The Journal of …, 2013 - academic.oup.com
Introduction Measurement of testis volume (TV) is a reliable clinical procedure that predicts
reproductive fitness. However, the role of TV in overall and cardiovascular (CV) fitness has …