Rapid and simultaneous multiepitope antigen-based detection of Enterococcus by microscale thermophoresis and immunomagnetic separation

Y Liu, Z Wang, Z Wang, J Zhou, J Han, C Lu… - Frontiers in …, 2024 - frontiersin.org
Background Generally, enterococci bacteria cause nosocomial infections and are major
indicators of bacterial contamination in marine bathing beach. However, a method for the …

Ageing of Plasmodium falciparum malaria sporozoites alters their motility, infectivity and reduces immune activation in vitro

R van Schuijlenburg, S Azargoshasb, CM de Korne… - Malaria Journal, 2024 - Springer
Background Sporozoites (SPZ), the infective form of Plasmodium falciparum malaria, can be
inoculated into the human host skin by Anopheline mosquitoes. These SPZ migrate at …

A guide to investigating immune responses elicited by whole‐sporozoite pre‐erythrocytic vaccines against malaria

D Moita, H Nunes‐Cabaço, AM Mendes… - The FEBS …, 2022 - Wiley Online Library
In the last few decades, considerable efforts have been made toward the development of
efficient vaccines against malaria. Whole‐sporozoite (Wsp) vaccines, which induce efficient …

Role of nanotechnology against malaria: current perspectives and strategies

S Gupta, CE Umeyor, VB Patravale - … for the Prevention and Treatment of …, 2023 - Springer
Numerous malaria treatments have been proposed for over a century, but they have
consistently failed to eradicate the disease. This is mainly due to the development of drug …

A 2D GaAs-Based Photonic Crystal Biosensor for Malaria Detection.

S Raga, SK Gowre, H Miyan - International Journal of …, 2023 - search.ebscohost.com
Gallium arsenide (GaAs) composite semi-conductive rods with an air background lattice act
as the building blocks for the photonic crystal structure used of a biosensor. The study …

Malaria: Paving the way to developing peptide-based vaccines against invasion in infectious diseases

C Reyes, J Molina-Franky, J Aza-Conde… - Biochemical and …, 2020 - Elsevier
Malaria remains a large-scale public health problem, killing more than 400,000 people and
infecting up to 230 million worldwide, every year. Unfortunately, despite numerous efforts …

Subcutaneous immunization with unaltered axenic malaria parasite liver stages induces sterile protection against infectious Sporozoite challenge

M Kamil, G Deveci, UY Kina, SHI Kappe, ASI Aly - Vaccines, 2022 - mdpi.com
Host cell-free, axenic development of liver stages (LS) of the malaria parasite has been
demonstrated. Here we explored axenic liver stages as a novel live whole parasite malaria …

[HTML][HTML] Diversity and selection analyses identify transmission-blocking antigens as the optimal vaccine candidates in Plasmodium falciparum

II Ciubotariu, BK Broyles, S Xie, J Thimmapuram… - medRxiv, 2024 - ncbi.nlm.nih.gov
Background A highly effective vaccine for malaria remains an elusive target, at least in part
due to the under-appreciated natural parasite variation. This study aimed to investigate …

High-performance two-dimensional photonic crystal biosensor to diagnose malaria infected RBCs

H Tayoub, A Hocini, A Harhouz - 2023 - essuir.sumdu.edu.ua
In this paper, a two-dimensional photonic crystal refractive index biosensor based on a ring-
shaped cavity has been proposed. It is designed for the diagnosis of malaria-infected red …

Identification, Selection and Immune Assessment of Liver Stage CD8 T Cell Epitopes From Plasmodium falciparum

KD Tucker, BC Schanen, TW Phares… - Frontiers in …, 2021 - frontiersin.org
Immunization with radiation-attenuated sporozoites (RAS) has been shown to protect
against malaria infection, primarily through CD8 T cell responses, but protection is limited …