Anti-Inflammatory Therapeutic Mechanisms of Isothiocyanates: Insights from Sulforaphane

S Habtemariam - Biomedicines, 2024 - mdpi.com
Isothiocyanates (ITCs) belong to a group of natural products that possess a highly reactive
electrophilic− N= C= S functional group. They are stored in plants as precursor molecules …

Plant-Derived Epi-Nutraceuticals as Potential Broad-Spectrum Anti-Viral Agents

R Gabbianelli, E Shahar, G De Simone, C Rucci… - Nutrients, 2023 - mdpi.com
Although the COVID-19 pandemic appears to be diminishing, the emergence of SARS-CoV-
2 variants represents a threat to humans due to their inherent transmissibility, immunological …

Two new and effective food-extracted immunomodulatory agents exhibit anti-inflammatory response activity in the hACE2 acute lung injury murine model of COVID-19

S Liu, B Wang, T Chen, H Wang, J Liu, X Zhao… - Frontiers in …, 2024 - frontiersin.org
Objective The coronavirus disease 2019 (COVID-19) spread rapidly and claimed millions of
lives worldwide. Acute respiratory distress syndrome (ARDS) is the major cause of COVID …

Animal efficacy study of a plant extract complex (BEN815) as a potential treatment for COVID-19

MH Do, H Li, SY Cho, S Oh, JH Jeong, MS Song… - Plos one, 2023 - journals.plos.org
In a short time, several types of injectable and oral therapeutics have been developed and
used to effectively manage patients with coronavirus disease 2019 (COVID-19). BEN815 is …

SFX-01 in hospitalised patients with community-acquired pneumonia during the COVID-19 pandemic: a double-blind, randomised, placebo-controlled trial

MB Long, H Abo-Leyah, YH Giam… - ERJ Open …, 2024 - Eur Respiratory Soc
Introduction Sulforaphane can induce the transcription factor, Nrf2, promoting antioxidant
and anti-inflammatory responses. In this study, hospitalised patients with community …

Phytochemicals and micronutrients in suppressing infectivity caused by SARS-CoV-2 virions and seasonal coronavirus HCoV-229E in vivo

A Goc, W Sumera, M Rath… - European Journal of …, 2023 - akjournals.com
SARS-CoV-2 infection still poses health threats especially to older and
immunocompromised individuals. New emerging variants of SARS-CoV-2, including …

Isolation, characterization and SARS-CoV-2 3CL protease inhibitory activity of a new methylsulfinyl-butanyl derivative from Raphani Semen

H Wang, B Chi, C Li, Z Tian, Y Liu - Natural Product Research, 2024 - Taylor & Francis
A new compound named raphanised A (1), along with two known methylsulfinyl-butanyl
derivatives (2-3) and seven known indole derivatives (4-10), were isolated from the Raphani …

Bioactive Compounds from Food and Its By-products: Current Applications and Future Perspectives

BR de Albuquerque, RCG Corrêa… - Food Waste …, 2023 - Springer
Foods are important for the supply of essential nutrients to the body, but they can also be
sources of bioactive molecules, such as phenolic compounds, alkaloids, glucosinolates, and …

Multi-target mode of action of Sulfodyne®, a stabilized Sulforaphane, against pathogenic effects of SARS-CoV-2 infection

PH Romeo, L Conquet, S Messiaen, Q Pascal… - bioRxiv, 2023 - biorxiv.org
The coronavirus disease 2019 (COVID-19) due to the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has shown that, except vaccination, few therapeutics options …

Plant Immunoenhancers: Promising Ethnopharmacological Candidates for Anti-SARS-CoV-2 Activity

S Hafez Ghoran, F Taktaz, SA Ayatollahi - … for COVID-19: Anti-SARS-CoV …, 2023 - Springer
Medicinal plants have gained attention for their bioactive phytochemicals, affordability,
patient-friendly nature, and avoidance of synthetic drug side effects. Over the past 3 years …