[HTML][HTML] Metformin: update on mechanisms of action and repurposing potential

M Foretz, B Guigas, B Viollet - Nature Reviews Endocrinology, 2023 - nature.com
Currently, metformin is the first-line medication to treat type 2 diabetes mellitus (T2DM) in
most guidelines and is used daily by> 200 million patients. Surprisingly, the mechanisms …

A global view of the interplay between non-alcoholic fatty liver disease and diabetes

N Stefan, K Cusi - The lancet Diabetes & endocrinology, 2022 - thelancet.com
Non-alcoholic fatty liver disease (NAFLD) has become an epidemic, much like other non-
communicable diseases (NCDs), such as cancer, obesity, diabetes, and cardiovascular …

[HTML][HTML] A wearable electrochemical biosensor for the monitoring of metabolites and nutrients

M Wang, Y Yang, J Min, Y Song, J Tu… - Nature Biomedical …, 2022 - nature.com
Wearable non-invasive biosensors for the continuous monitoring of metabolites in sweat can
detect a few analytes at sufficiently high concentrations, typically during vigorous exercise so …

An update on the epidemiology of type 2 diabetes: a global perspective

MG Tinajero, VS Malik - Endocrinology and Metabolism Clinics, 2021 - endo.theclinics.com
Type 2 diabetes (T2D) is a chronic health condition that has reached alarming rates across
the globe. A little more than 2 decades ago, the International Diabetes Federation (IDF) …

COVID-19 and metabolic disease: mechanisms and clinical management

C Steenblock, PEH Schwarz, B Ludwig… - The lancet Diabetes & …, 2021 - thelancet.com
Up to 50% of the people who have died from COVID-19 had metabolic and vascular
disorders. Notably, there are many direct links between COVID-19 and the metabolic and …

[HTML][HTML] Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19

F Karagiannis, K Peukert, L Surace, M Michla… - Nature, 2022 - nature.com
Anorexia and fasting are host adaptations to acute infection, and induce a metabolic switch
towards ketogenesis and the production of ketone bodies, including β-hydroxybutyrate …

[HTML][HTML] Pharmacological inhibition of fatty acid synthesis blocks SARS-CoV-2 replication

J Chu, C Xing, Y Du, T Duan, S Liu, P Zhang… - Nature …, 2021 - nature.com
Caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), COVID-19 is a
virus-induced inflammatory disease of the airways and lungs that leads to severe multi …

[HTML][HTML] Multidisciplinary collaborative consensus guidance statement on the assessment and treatment of fatigue in postacute sequelae of SARS‐CoV‐2 infection …

JE Herrera, WN Niehaus, J Whiteson, A Azola… - Pm & R, 2021 - ncbi.nlm.nih.gov
Large numbers of individuals who have been infected with SARS-CoV-2, the virus
responsible for COVID-19, continue to experience a constellation of symptoms long past the …

[HTML][HTML] Innate metabolic responses against viral infections

CS Palmer - Nature Metabolism, 2022 - nature.com
Metabolic adaptation to viral infections critically determines the course and manifestations of
disease. At the systemic level, a significant feature of viral infection and inflammation that …

[HTML][HTML] Association of vitamin D status with COVID-19 and its severity: Vitamin D and COVID-19: A narrative review

JH Bae, HJ Choe, MF Holick, S Lim - Reviews in Endocrine and Metabolic …, 2022 - Springer
Vitamin D is associated with biological activities of the innate and adaptive immune systems,
as well as inflammation. In observational studies, an inverse relationship has been found …