The biosynthetic secretory pathway is comprised of multiple steps, modifications and
interactions that form a highly precise pathway of protein trafficking and secretion, that is …

Background: Idiopathic pulmonary fibrosis (IPF) is a rare and severe disease with a median
survival of∼ 3 years. Several risk factors have been identified, such as age, genetic …

A defining pathological feature of human lung fibrosis is localized tissue heterogeneity,
which challenges the interpretation of transcriptomic studies that typically lose spatial …

Hyperoxia disrupts lung development in mice and causes bronchopulmonary dysplasia
(BPD) in neonates. To investigate sex-dependent molecular and cellular programming …

Idiopathic pulmonary fibrosis (IPF) is marked by the activation of fibroblasts, leading to
excessive production and deposition of extracellular matrix (ECM) within the lung …

Honeycombing is a histological pattern consistent with Usual Interstitial Pneumonia (UIP).
Honeycombing refers to cystic airways located at sites of dense fibrosis with marked mucus …

Background The severity of COVID-19 is influenced by various factors including the
presence of respiratory diseases. Studies have indicated a potential relationship between …

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease that is often fatal
due to the formation of irreversible scar tissue in the distal areas of the lung. Although the …

Human diseases are characterized by intricate cellular dynamics. Single-cell sequencing
provides critical insights, yet a persistent gap remains in computational tools for detailed …

Background: Idiopathic pulmonary fibrosis (IPF) is a life-threatening disease whose etiology
remains unknown. This study aims to explore diagnostic biomarkers and pathways involved …