Drug design strategies that aim to improve the low solubility and poor bioavailability conundrum in quercetin derivatives

SR Alizadeh, N Savadkouhi… - Expert Opinion on Drug …, 2023 - Taylor & Francis
Introduction Scientists are especially interested in polyphenols, particularly flavonoids.
Quercetin, a flavonoid, has demonstrated various therapeutic properties, such as …

Multifunctional and theranostic hydrogels for wound healing acceleration: An emphasis on diabetic-related chronic wounds

PM Tehrany, P Rahmanian, A Rezaee… - Environmental …, 2023 - Elsevier
Hydrogels represent intricate three-dimensional polymeric structures, renowned for their
compatibility with living systems and their ability to naturally degrade. These networks stand …

Synthesis and Evaluation of Rutin–Hydroxypropyl β-Cyclodextrin Inclusion Complexes Embedded in Xanthan Gum-Based (HPMC-g-AMPS) Hydrogels for Oral …

A Naeem, C Yu, Z Zang, W Zhu, X Deng, Y Guan - Antioxidants, 2023 - mdpi.com
Oxidants play a significant role in causing oxidative stress in the body, which contributes to
the development of diseases. Rutin—a powerful antioxidant—may be useful in the …

Supramolecular β-Cyclodextrin-Quercetin Based Metal–Organic Frameworks as an Efficient Antibiofilm and Antifungal Agent

R Rajamohan, CJ Raorane, SC Kim, MM Krishnan… - Molecules, 2023 - mdpi.com
The loading of drugs or medicinally active compounds has recently been performed using
metal–organic frameworks (MOFs), which are thought to be a new type of porous material in …

Enhancing the bioavailability of quercetin via the construction of carboxymethylated curdlan/quercetin nanocomplex

Y Su, Q Zhou, H Xu, M Huang, S Li, J He, KW Cheng… - Food …, 2024 - Elsevier
Quercetin, renowned for its antioxidant and anti-inflammatory properties, holds promise for
promoting human health. However, its limited solubility and stability hinders the bioactive …

Multifunctional extracellular matrix hydrogel with self-healing properties and promoting angiogenesis as an immunoregulation platform for diabetic wound healing

Z Sun, H Xiong, T Lou, W Liu, Y Xu, S Yu, H Wang… - Gels, 2023 - mdpi.com
Treating chronic wounds is a global challenge. In diabetes mellitus cases, long-time and
excess inflammatory responses at the injury site may delay the healing of intractable …

Biodegradable film of carboxymethyl cellulose modified with red onion peel powder waste and boron nitride nanoparticles: Investigation of physicochemical properties …

S Pirsa, M Bener, FB Şen - Food Chemistry, 2024 - Elsevier
The aim of this study was to modify carboxymethyl cellulose (CMC) films with onion peel
extract (OPE)(0–2 g), onion peel powder (OPP)(0–2 g) and boron nitride nanoparticles …

β-Cyclodextrin-assisted mechanical inclusion extraction of lipophilic flavonoids and hydrophilic terpenoids from functional food

Y Shi, HF Jin, YW Wu, SC Zhu, J Cao - Food Chemistry, 2024 - Elsevier
This study presents an innovative, efficient, environmentally friendly and rapid mechanical
inclusion extraction (MIE) method for active ingredients in functional food. 2-hydroxypropyl …

Preparation and characterization of a nano-inclusion complex of quercetin with β-cyclodextrin and its potential activity on cancer cells

R Rajamohan, S Ashokkumar, K Murugavel, YR Lee - Micromachines, 2023 - mdpi.com
Quercetin (QRC), a flavonoid found in foods and plants such as red wine, onions, green tea,
apples, and berries, possesses remarkable anti-inflammatory and antioxidant properties …

[HTML][HTML] Hydrogel wound dressings containing bioactive compounds originated from traditional Chinese herbs: A review

D Yang, H Chen, H Wei, A Liu, DX Wei… - Smart Materials in …, 2023 - Elsevier
Various factors can cause skin defects, resulting in the loss of physiological functions and
even death due to severe concurrent infection. Dressings are often clinically used to fully …