Towards reproducible brain-wide association studies
Magnetic resonance imaging (MRI) continues to drive many important neuroscientific
advances. However, progress in uncovering reproducible associations between individual …
advances. However, progress in uncovering reproducible associations between individual …
Considerations toward an epigenetic and common pathways theory of mental disorder.
JT Nigg - Journal of Psychopathology and Clinical Science, 2023 - psycnet.apa.org
Psychopathology emerges from the dynamic interplay of physiological and mental
processes and ecological context. It can be seen as a failure of recursive, homeostatic …
processes and ecological context. It can be seen as a failure of recursive, homeostatic …
[HTML][HTML] Generalization of cortical MOSTest genome-wide associations within and across samples
Abstract Genome-Wide Association studies have typically been limited to univariate analysis
in which a single outcome measure is tested against millions of variants. Recent work …
in which a single outcome measure is tested against millions of variants. Recent work …
Cumulative effects of resting-state connectivity across all brain networks significantly correlate with ADHD symptoms
Background The clinical utility of MRI neuroimaging studies of psychopathology has been
limited by a constellation of factors—small sample sizes, small effect sizes, and …
limited by a constellation of factors—small sample sizes, small effect sizes, and …
Fluid and crystallised intelligence are associated with distinct regionalisation patterns of cortical morphology
Cognitive performance in children is predictive of academic and social outcomes; therefore,
understanding neurobiological mechanisms underlying individual differences in cognition …
understanding neurobiological mechanisms underlying individual differences in cognition …
Determining the association between regionalisation of cortical morphology and cognition in 10,145 children
Individuals undergo protracted changes in cortical morphology during childhood and
adolescence, coinciding with cognitive development. Studies quantifying the association …
adolescence, coinciding with cognitive development. Studies quantifying the association …
A Bayesian Regularized and Anotation-Informed Integrative Analysis of Cognition (BRAINIAC)
Here we present a development of the novel Bayesian Regularized and Anotation-Informed
Integrative Analysis of Cognition (BRAINIAC) model. BRAINIAC allows for both estimation of …
Integrative Analysis of Cognition (BRAINIAC) model. BRAINIAC allows for both estimation of …
Efficient meta-analysis of multivariate genome-wide association studies with Meta-MOSTest
Motivation Genome-wide association studies (GWAS) have been successful in identifying
genetic variants associated with a particular phenotype. However, many complex …
genetic variants associated with a particular phenotype. However, many complex …