Healthy aging and human longevity are intricate phenotypes affected by environmental
factors such as physical exercise, diet, health habits, and psychosocial situations as well as …

Aging is the leading risk factor for several age-associated diseases such as
neurodegenerative diseases. Understanding the biology of aging mechanisms is essential …

Impaired immune function has been implicated in the declining health and higher incidence
of cancer in the elderly. However, age-related changes to immunity are not completely …

Praised forits clarity of presentation and accessibility, Introduction to Modern Virology has
been a successful student text for over 30 years. It provides a broad introduction to virology …

There exists a phenomenon in aging research whereby early life stress can have positive
impacts on longevity. The mechanisms underlying these observations suggest a robust, long …

Elderly individuals are at high risk for morbidity and mortality when infected with influenza
virus. Vaccinations with inactivated virus are less effective in the elderly due to the declining …

[Frontiers in Bioscience 7, d1056-1183, May 1, 2002] 1056 T CELLS AND AGING,
JANUARY 2002 UPDATE Graham Pawelec1, Yvonne Barnett Page 1 [Frontiers in …

Immunosenescence is a process that primarily affects the T cell compartment of the immune
system, although age-associated immunological alterations have also been demonstrated in …

Natural killer (NK) cells are cytotoxic cells that play a critical role in the innate immune
response against infections and tumors. Recent studies on NK cell biology have …

Infectious diseases are major causes, with malignancies, of morbidity and mortality in the
elderly. Increased susceptibility to infections may result from underlying dysfunction of an …