[HTML][HTML] SARS-CoV-2/COVID-19: viral genomics, epidemiology, vaccines, and therapeutic interventions
The COVID-19 pandemic is due to infection caused by the novel SARS-CoV-2 virus that
impacts the lower respiratory tract. The spectrum of symptoms ranges from asymptomatic …
impacts the lower respiratory tract. The spectrum of symptoms ranges from asymptomatic …
Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development
The recent outbreak of the betacoronavirus SARS-CoV-2 has become a significant concern
to public health care worldwide. As of August 19, 2020, more than 22,140,472 people are …
to public health care worldwide. As of August 19, 2020, more than 22,140,472 people are …
TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes
R Zang, MFG Castro, BT McCune, Q Zeng… - Science …, 2020 - science.org
Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA are frequently observed
in COVID-19. However, it is unclear whether SARS-CoV-2 replicates in the human intestine …
in COVID-19. However, it is unclear whether SARS-CoV-2 replicates in the human intestine …
Evidence of structural protein damage and membrane lipid remodeling in red blood cells from COVID-19 patients
T Thomas, D Stefanoni, M Dzieciatkowska… - Journal of proteome …, 2020 - ACS Publications
The SARS-CoV-2 beta coronavirus is the etiological driver of COVID-19 disease, which is
primarily characterized by shortness of breath, persistent dry cough, and fever. Because they …
primarily characterized by shortness of breath, persistent dry cough, and fever. Because they …
[HTML][HTML] COVID-19 in the heart and the lungs: could we “Notch” the inflammatory storm?
From January 2020, coronavirus disease (COVID-19) originated in China has spread
around the world. The disease is caused by the severe acute respiratory syndrome …
around the world. The disease is caused by the severe acute respiratory syndrome …
Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion
Cholesterol 25-hydroxylase (CH25H) is an interferon (IFN)-stimulated gene that shows
broad antiviral activities against a wide range of enveloped viruses. Here, using an IFN …
broad antiviral activities against a wide range of enveloped viruses. Here, using an IFN …
[PDF][PDF] Functional landscape of SARS-CoV-2 cellular restriction
L Martin-Sancho, MK Lewinski, L Pache, CA Stoneham… - Molecular cell, 2021 - cell.com
A deficient interferon (IFN) response to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection has been implicated as a determinant of severe coronavirus …
(SARS-CoV-2) infection has been implicated as a determinant of severe coronavirus …
Potential therapeutic targets for combating SARS-CoV-2: Drug repurposing, clinical trials and recent advancements
A Pandey, AN Nikam, AB Shreya, SP Mutalik… - Life sciences, 2020 - Elsevier
The present pandemic of SARS-CoV-2 has been a tough task for the whole world to deal
with. With the absence of specific drugs or vaccines against SARS-CoV-2, the situation is …
with. With the absence of specific drugs or vaccines against SARS-CoV-2, the situation is …
[HTML][HTML] Structural and non-structural proteins in SARS-CoV-2: potential aspects to COVID-19 treatment or prevention of progression of related diseases
S Kakavandi, I Zare, M VaezJalali, M Dadashi… - Cell Communication and …, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is caused by a new member of the
Coronaviridae family known as severe acute respiratory syndrome coronavirus 2 (SARS …
Coronaviridae family known as severe acute respiratory syndrome coronavirus 2 (SARS …
[HTML][HTML] Vimentin as a multifaceted player and potential therapeutic target in viral infections
Vimentin is an intermediate filament protein that plays key roles in integration of cytoskeletal
functions, and therefore in basic cellular processes such as cell division and migration …
functions, and therefore in basic cellular processes such as cell division and migration …