Alcoholic liver disease (ALD) is a globally prevalent chronic liver disease caused by chronic
or binge consumption of alcohol. The therapeutic efficiency of current therapies for ALD is …

Glucocorticoid-induced osteonecrosis of the femoral head (GIONFH) is the main
complication secondary to long-term or excessive glucocorticoid use. Promoting …

Neurological disorders represent a global health problem. Current pharmacological
treatments often lead to short-term symptomatic relief but have dose-dependent side effects …

Directional differentiation of stem cells is a key step in stem cell therapy. In this study, we
developed saponin-based nanoparticles (Ad-SNPs) containing dexamethasone (Dex) and …

Ischemic stroke (IS) causes severe disability and high mortality worldwide. Stem cell (SC)
therapy exhibits unique therapeutic potential for IS that differs from current treatments. SC's …

A typical condition of the female reproductive system is polycystic ovary syndrome (PCOS).
Hyperinsulinemia, insulin resistance, obesity, and hyperandrogenism are just a few of the …

Brain injuries due to trauma or stroke are major causes of adult death and disability.
Unfortunately, few interventions are effective for post-injury repair of brain tissue. After a long …

Coronavirus disease 2019 (COVID-19), the pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), which counts more than 650 million cases and …

The need for bone substitutes is a major challenge as the incidence of serious bone
disorders is massively increasing, mainly attributed to modern world problems, such as …

Introduction Cyclosporine (CsA), a potent immunosuppressive chemotherapeutic
medication, treats numerous cancers, particularly malignant carcinoma, acute leukemia, and …