Understanding the Intricacies of Cellular Senescence in Atherosclerosis: Mechanisms and Therapeutic Implications

I Ali, H Zhang, SAA Zaidi, G Zhou - Ageing Research Reviews, 2024 - Elsevier
Cardiovascular disease is currently the largest cause of mortality and disability globally,
surpassing communicable diseases, and atherosclerosis is the main contributor to this …

Untethered Microgrippers for Precision Medicine

H Zhou, S Zhang, Z Liu, B Chi, J Li, Y Wang - Small, 2024 - Wiley Online Library
Microgrippers, a branch of micro/nanorobots, refer to motile miniaturized machines that are
of a size in the range of several to hundreds of micrometers. Compared with tethered …

Localized immunomodulation technologies to enable cellular and organoid transplantation

A Nash, N Lokhorst, O Veiseh - Trends in Molecular Medicine, 2023 - cell.com
Localized immunomodulation technologies are rapidly emerging as a new modality with the
potential to revolutionize transplantation of cells and organs. In the past decade, cell-based …

A bioengineered artificial interstitium supports long-term islet xenograft survival in nonhuman primates without immunosuppression

SH Oppler, LL Hocum Stone, DJ Leishman… - Science …, 2024 - science.org
Cell-based therapies hold promise for many chronic conditions; however, the continued
need for immunosuppression along with challenges in replacing cells to improve durability …

Mechanisms of potential therapeutic utilization of mesenchymal stem cells in COVID-19 treatment

Y Fang, P Lao, L Tang, J Chen, Y Chen… - Cell …, 2023 - journals.sagepub.com
The 2019 novel coronavirus disease (COVID-19) has lasted for over 3 years and has
seriously affected the regular life trajectory of human beings. The severe acute respiratory …

Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH

S Yao, Z Zhou, L Wang, H Lv, D Liu, Q Zhu, X Zhang… - Iscience, 2023 - cell.com
Intrauterine adhesion (IUA) is a common cause of uterine infertility and its histopathologic
characteristic is endometrial fibrosis. A shortage of stem cells in the endometrial basalis has …

Research progress in cell therapy for oral diseases: Focus on cell sources and strategies to optimize cell function

J Wang, Z Zhao, K Yang, Y Bai - Frontiers in Bioengineering and …, 2024 - frontiersin.org
In recent years, cell therapy has come to play an important therapeutic role in oral diseases.
This paper reviews the active role of mesenchymal stem cells, immune cell sources, and …

Carbon Quantum Dots as Multi‐Purpose Nanomaterial in Stem Cell Therapy

K Bahrampour Juybari, K Rizwan… - Chemistry & …, 2023 - Wiley Online Library
During stem cell therapy, some issues, such as obscure fate of stem cells or their low
survival rate in the body, should be addressed to boost their therapeutic efficiency …

Microengineered in vitro assays for screening and sorting manufactured therapeutic T cells

AK Muhuri, Y Alapan, CP Camargo… - The Journal of …, 2024 - journals.aai.org
Adoptively transferred T cells constitute a major class of current and emergent cellular
immunotherapies for the treatment of disease, including but not limited to cancer. Although …

An insight into the prospects and drawbacks of stem cell therapy for spinal cord injuries: ongoing trials and future directions

SI Khan, N Ahmed, K Ahsan, M Abbasi, R Maugeri… - Brain Sciences, 2023 - mdpi.com
Spinal cord injury (SCI) is a devastating neurological disorder that has a substantial
detrimental impact on a person's quality of life. The estimated global incidence of SCI is 40 …