Epilepsy is a chronic disease that affects millions of people worldwide. Antiepileptic drugs
(AEDs) are used to control seizures. Even though parts of their mechanisms of action are …

Excitatory amino acid transporters (EAATs) encompass a class of five transporters with
distinct expression in neurons and glia of the central nervous system (CNS). EAATs are …

Antibiotic resistance is a severe global threat for public health, causing around 700,000
deaths per year. Horizontal gene transfer (HGT) is one of the most significant pathways to …

Introduction: The brain is particularly susceptible to oxidative stress being the most
aerobically active organ in the body due to its high metabolic demands. There is evidence …

Nowadays, the worldwide interest is growing to use medicinal plants and their active
constituents to develop new potent medicines with fewer side effects. Precise dietary …

Epilepsy is one of the most common neurological disorders that severely affect life quality of
many people worldwide. Ion transport in the neuronal membrane, inhibitory–excitatory …

In diseases of the central nervous system, such as Alzheimer's disease (AD), Parkinson's
disease (PD), stroke, amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), and …

Reactive species are produced in biological system because of redox reactions. The
imbalance in pro-oxidant and antioxidant homeostasis leads to the production of toxic …

Neurological disorders are the major cause of disability, leading to a decrease in quality of
life by impairing cognitive, sensorimotor, and motor functioning. Several factors have been …

Background Neuroinflammation with activation of microglia and production of
proinflammatory cytokines in the brain plays an active role in epileptic disorders. Brain …