Reevaluation by the CRISPR/Cas9 knockout approach revealed that multiple pluripotency-associated lncRNAs are dispensable for pluripotency maintenance while …
Z Li, X Li, J Lin, Y Wang, H Cao, J Zhou - Science China Life Sciences, 2024 - Springer
Many long noncoding RNAs (lncRNAs) have been identified through siRNA-based
screening as essential regulators of embryonic stem cell (ESC) pluripotency. However, the …
screening as essential regulators of embryonic stem cell (ESC) pluripotency. However, the …
Di-and tri-methylation of histone H3K36 play distinct roles in DNA double-strand break repair
R Chen, MJ Zhao, YM Li, AH Liu, RX Wang… - Science China Life …, 2024 - Springer
Abstract Histone H3 Lys36 (H3K36) methylation and its associated modifiers are crucial for
DNA double-strand break (DSB) repair, but the mechanism governing whether and how …
DNA double-strand break (DSB) repair, but the mechanism governing whether and how …
KLF4 promotes milk fat synthesis by regulating the PI3K-AKT-mTOR pathway and targeting FASN activation in bovine mammary epithelial cells
HY Wu, ZH Ji, WY Xie, HX Guo, Y Zheng, W Gao… - Iscience, 2024 - cell.com
Milk fat is an important indicator for evaluating the quality of cow's milk. In this study, we used
bovine mammary epithelial cells (BMECs) to investigate the role and molecular mechanism …
bovine mammary epithelial cells (BMECs) to investigate the role and molecular mechanism …
Single-Cell RNA Sequencing Reveals Differences in Chromatin Remodeling and Energy Metabolism among In Vivo-Developed, In Vitro-Fertilized, and …
J Fan, C Liu, Y Zhao, Q Xu, Z Yin, Z Liu, Y Mu - Animals, 2024 - mdpi.com
Simple Summary This study investigated the developmental differences between in vivo-
developed (IVV) and in vitro embryos (in vitro fertilization (IVF) and parthenogenetic …
developed (IVV) and in vitro embryos (in vitro fertilization (IVF) and parthenogenetic …