SELEX: Critical factors and optimization strategies for successful aptamer selection

M Kohlberger, G Gadermaier - Biotechnology and applied …, 2022 - Wiley Online Library
Within the last decade, the application range of aptamers in biochemistry and medicine has
expanded rapidly. More than just a replacement for antibodies, these intrinsically structured …

Advanced materials-integrated electrochemical sensors as promising medical diagnostics tools: A review

K Nemčeková, J Labuda - Materials Science and Engineering: C, 2021 - Elsevier
Electrochemical sensors have increasingly been linked with terms as modern biomedically
effective highly selective and sensitive devices, wearable and wireless technology, portable …

Quantum plasmonics pushes chiral sensing limit to single molecules: a paradigm for chiral biodetections

C Zhang, H Hu, C Ma, Y Li, X Wang, D Li… - Nature …, 2024 - nature.com
Chiral sensing of single molecules is vital for the understanding of chirality and their
applications in biomedicine. However, current technologies face severe limitations in …

Solid-state and polymer nanopores for protein sensing: A review

N Meyer, I Abrao-Nemeir, JM Janot, J Torrent… - Advances in colloid and …, 2021 - Elsevier
In two decades, the solid state and polymer nanopores became attractive method for the
protein sensing with high specificity and sensitivity. They also allow the characterization of …

Biological nanopores: Engineering on demand

A Crnković, M Srnko, G Anderluh - Life, 2021 - mdpi.com
Nanopore-based sensing is a powerful technique for the detection of diverse organic and
inorganic molecules, long-read sequencing of nucleic acids, and single-molecule analyses …

Smart approach for the design of highly selective aptamer-based biosensors

A Douaki, D Garoli, AKMS Inam, MAC Angeli… - Biosensors, 2022 - mdpi.com
Aptamers are chemically synthesized single-stranded DNA or RNA oligonucleotides widely
used nowadays in sensors and nanoscale devices as highly sensitive biorecognition …

Detection of small-sized DNA fragments in a glassy nanopore by utilization of CRISPR-Cas12a as a converter system

S Zhang, M Liu, H Cui, MA Ziaee, R Sun, L Chen… - Analyst, 2022 - pubs.rsc.org
The fabrication of nanopores with a matched pore size, and the existence of multiple
interferents make the reproducible detection of small-sized molecules by means of solid …

Biological nanopores for sensing applications

M Zhang, C Chen, Y Zhang… - … : Structure, Function, and …, 2022 - Wiley Online Library
Biological nanopores are proteins with transmembrane pore that can be embedded in lipid
bilayer. With the development of single‐channel current measurement technologies …

Bioinspired Solid‐State Nanochannel Sensors: From Ionic Current Signals, Current, and Fluorescence Dual Signals to Faraday Current Signals

D Zhang, X Zhang - Small, 2021 - Wiley Online Library
Inspired from bioprotein channels of living organisms, constructing “abiotic” analogues, solid‐
state nanochannels, to achieve “smart” sensing towards various targets, is highly seductive …

Nanopore-based aptasensor for label-free and sensitive vanillin determination in food samples

MA Elaguech, M Bahri, K Djebbi, D Zhou, B Shi… - Food Chemistry, 2022 - Elsevier
Dielectric breakdown technique was utlised to fabricate 5–6 nm nanopores for vanillin
detection in various food samples. A highly selective aptamer (Van_74) with high binding …