Mitochondrial control of inflammation
Numerous mitochondrial constituents and metabolic products can function as damage-
associated molecular patterns (DAMPs) and promote inflammation when released into the …
associated molecular patterns (DAMPs) and promote inflammation when released into the …
Critical determinants of cytokine storm and type I interferon response in COVID-19 pathogenesis
S Ramasamy, S Subbian - Clinical microbiology reviews, 2021 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19), a rapidly evolving pandemic worldwide with at least 68 million …
disease 2019 (COVID-19), a rapidly evolving pandemic worldwide with at least 68 million …
The cGAS–STING pathway drives type I IFN immunopathology in COVID-19
JD Domizio, MF Gulen, F Saidoune, VV Thacker… - Nature, 2022 - nature.com
COVID-19, which is caused by infection with SARS-CoV-2, is characterized by lung
pathology and extrapulmonary complications,. Type I interferons (IFNs) have an essential …
pathology and extrapulmonary complications,. Type I interferons (IFNs) have an essential …
Activation of NF-κB and induction of proinflammatory cytokine expressions mediated by ORF7a protein of SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent for
coronavirus disease 2019 (COVID-19) that emerged in human populations recently …
coronavirus disease 2019 (COVID-19) that emerged in human populations recently …
Integrative imaging reveals SARS-CoV-2-induced reshaping of subcellular morphologies
Pathogenesis induced by SARS-CoV-2 is thought to result from both an inflammation-
dominated cytokine response and virus-induced cell perturbation causing cell death. Here …
dominated cytokine response and virus-induced cell perturbation causing cell death. Here …
Roles and functions of SARS-CoV-2 proteins in host immune evasion
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evades the host immune
system through a variety of regulatory mechanisms. The genome of SARS-CoV-2 encodes …
system through a variety of regulatory mechanisms. The genome of SARS-CoV-2 encodes …
SARS‐CoV‐2 sensing by RIG‐I and MDA5 links epithelial infection to macrophage inflammation
LG Thorne, AK Reuschl, L Zuliani‐Alvarez… - The EMBO …, 2021 - embopress.org
SARS‐CoV‐2 infection causes broad‐spectrum immunopathological disease, exacerbated
by inflammatory co‐morbidities. A better understanding of mechanisms underpinning virus …
by inflammatory co‐morbidities. A better understanding of mechanisms underpinning virus …
NF-κB pathway as a potential target for treatment of critical stage COVID-19 patients
R Kircheis, E Haasbach, D Lueftenegger… - Frontiers in …, 2020 - frontiersin.org
Patients infected with SARS-CoV-2 show a wide spectrum of clinical manifestations ranging
from mild febrile illness and cough up to acute respiratory distress syndrome, multiple organ …
from mild febrile illness and cough up to acute respiratory distress syndrome, multiple organ …
Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19
Abstract In coronavirus disease 2019 (COVID-19), hypertension and cardiovascular
diseases are major risk factors for critical disease progression. However, the underlying …
diseases are major risk factors for critical disease progression. However, the underlying …
Can SARS-CoV-2 virus use multiple receptors to enter host cells?
LK Gadanec, KR McSweeney, T Qaradakhi… - International journal of …, 2021 - mdpi.com
The occurrence of the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
2), responsible for coronavirus disease 2019 (COVD-19), represents a catastrophic threat to …
2), responsible for coronavirus disease 2019 (COVD-19), represents a catastrophic threat to …