Abstract LC3-associated phagocytosis (LAP) is a novel form of non-canonical autophagy
where LC3 (microtubule-associated protein 1A/1B–light chain 3) is conjugated to …

Chronic inflammation in visceral adipose tissue (VAT) precipitates the development of
cardiometabolic disorders. Although changes in T cell function associated with visceral …

Background Sex differences in obesity and related diseases are well established. Gonadal
hormones are a major determinant of these sex differences. However, sex differences in …

The rising prevalence of childhood obesity has been postulated as an explanation for the
increasing rate of individuals diagnosed with type 1 diabetes (T1D). In this study, we use …

Obesity, insulin resistance, and type 1 diabetes mellitus : Current Opinion in Endocrinology,
Diabetes and Obesity Obesity, insulin resistance, and type 1 diabetes mellitus : Current Opinion …

The discovery of the archetypal adipocytokine leptin and how it regulates energy
homeostasis have represented breakthroughs in our understanding of the endocrine …

The association between smoke habit and autoimmunity has been hypothesized a long time
ago. Smoke has been found to play a pathogenic role in certain autoimmune disease as it …

Childhood obesity represents a worldwide concern as many countries have reported an
increase in its incidence, with possible cardiovascular long-term implications. The …

Background Obesity is over-represented in patients with psoriatic arthritis (PsA) and
associated with higher disease activity, poorer effect of treatment and increased …

Obesity-related insulin resistance is driven by low-grade chronic inflammation of metabolic
tissues. In the liver, nonalcoholic fatty liver disease (NAFLD) is associated with hepatic …