Adipose tissue (AT) regulates systemic insulin sensitivity through multiple mechanisms, and
alterations in de novo lipogenesis appear to contribute. Mice overexpressing GLUT4 in …

Multiple Sclerosis (MS) is an autoimmune disorder of the Central Nervous System that has
been associated with several environmental factors, such as diet and obesity. The possible …

Rheumatoid arthritis (RA) is a systemic chronic inflammatory disease characterized by
extensive synovitis resulting in erosions of articular cartilage and marginal bone with joint …

Patients with psoriatic arthritis (PsA) have a higher burden of cardio-metabolic comorbidities
like obesity, hypertension, diabetes, and cardiovascular disease compared to the general …

Although psoriasis has been associated with obesity, there are few prospective studies with
objective measures. We prospectively examined the effect of body mass index, waist …

Several studies conducted around the world over the last decade have demonstrated that
early childhood and adolescent obesity are significant risk factors for MS susceptibility. This …

Aims/hypothesis Excessive weight is a risk factor for type 2 diabetes, but its role in the
promotion of autoimmune diabetes is not clear. We investigated the risk of latent …

Psoriasis is chronic, immune-mediated, inflammatory disease with a multifactorial etiology
that affects the skin tissue and causes the appearance of dry and scaly lesions of anywhere …

Background The incidence of type 1 diabetes (T1D) is increasing globally. One hypothesis is
that increasing childhood obesity rates may explain part of this increase, but, as T1D is rare …

Changed dietary habits in Western countries such as reduced fiber intake represent an
important lifestyle factor contributing to the increase in inflammatory immune-mediated …