Phage display based biosensing: Recent advances and challenges
M Wang, S Pang, H Zhang, Z Yang, A Liu - TrAC Trends in Analytical …, 2024 - Elsevier
Phage display enables to screen probes such as peptide, antibody and nanobody with high
specificity and affinity to the target, providing excellent probes for various analytical or …
specificity and affinity to the target, providing excellent probes for various analytical or …
[HTML][HTML] Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B. 1.1. 7 variant
C Graham, J Seow, I Huettner, H Khan, N Kouphou… - Immunity, 2021 - cell.com
Interaction of the SARS-CoV-2 Spike receptor binding domain (RBD) with the receptor ACE2
on host cells is essential for viral entry. RBD is the dominant target for neutralizing …
on host cells is essential for viral entry. RBD is the dominant target for neutralizing …
Prevention and therapy of SARS-CoV-2 and the B. 1.351 variant in mice
Improving clinical care for individuals infected with SARS-CoV-2 variants is a global health
priority. Small-molecule antivirals like remdesivir (RDV) and biologics such as human …
priority. Small-molecule antivirals like remdesivir (RDV) and biologics such as human …
SARS-CoV-2 in animals: From potential hosts to animal models
A Michelitsch, K Wernike, L Ulrich… - Advances in Virus …, 2021 - Elsevier
Within only one year after the first detection of severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), nearly 100 million infections were reported in the human …
coronavirus-2 (SARS-CoV-2), nearly 100 million infections were reported in the human …
[HTML][HTML] Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding
D Mannar, JW Saville, X Zhu, SS Srivastava… - Cell Reports, 2021 - cell.com
The recently emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Beta
(B. 1.351) and Gamma (P. 1) variants of concern (VoCs) include a key mutation (N501Y) …
(B. 1.351) and Gamma (P. 1) variants of concern (VoCs) include a key mutation (N501Y) …
Isolation of a panel of ultra-potent human antibodies neutralizing SARS-CoV-2 and viral variants of concern
In the absence of virus-targeting small-molecule drugs approved for the treatment and
prevention of COVID-19, broadening the repertoire of potent SARS-CoV-2-neutralizing …
prevention of COVID-19, broadening the repertoire of potent SARS-CoV-2-neutralizing …
[HTML][HTML] Prophylaxis for COVID-19: a systematic review
M Smit, A Marinosci, T Agoritsas, A Calmy - Clinical microbiology and …, 2021 - Elsevier
Background While the landscape of vaccine and treatment candidates against the novel
coronavirus disease 2019 (COVID-19) has been reviewed systematically, prophylactic …
coronavirus disease 2019 (COVID-19) has been reviewed systematically, prophylactic …
SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface
F Bertoglio, D Meier, N Langreder, S Steinke… - Nature …, 2021 - nature.com
COVID-19 is a severe acute respiratory disease caused by SARS-CoV-2, a new recently
emerged sarbecovirus. This virus uses the human ACE2 enzyme as receptor for cell entry …
emerged sarbecovirus. This virus uses the human ACE2 enzyme as receptor for cell entry …
Therapeutic antibodies for COVID-19: is a new age of IgM, IgA and bispecific antibodies coming?
Early humoral immune responses to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are dominated by IgM and IgA antibodies, which greatly contribute to virus …
(SARS-CoV-2) are dominated by IgM and IgA antibodies, which greatly contribute to virus …
[HTML][HTML] Targeting protein-protein interaction interfaces in COVID-19 drug discovery
To date, the COVID-19 pandemic has claimed over 1 million human lives, infected another
50 million individuals and wreaked havoc on the global economy. The crisis has spurred the …
50 million individuals and wreaked havoc on the global economy. The crisis has spurred the …