Generation and utility of a single-chain fragment variable monoclonal antibody platform against a baculovirus expressed recombinant receptor binding domain of …
As the second wave of COVID-19 launched, various variants of Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) have emerged with a dramatic global spread …
Syndrome Coronavirus 2 (SARS-CoV-2) have emerged with a dramatic global spread …
A new era of antibody discovery: an in-depth review of AI-driven approaches
Highlights•This review paper underscores how recent advances in artificial intelligence,
particularly deep learning models, have revolutionized antibody design by accurately …
particularly deep learning models, have revolutionized antibody design by accurately …
XAV-19, a swine glyco-humanized polyclonal antibody against SARS-CoV-2 spike receptor-binding domain, targets multiple epitopes and broadly neutralizes variants
Amino acid substitutions and deletions in the Spike protein of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) variants can reduce the effectiveness of monoclonal …
syndrome coronavirus 2 (SARS-CoV-2) variants can reduce the effectiveness of monoclonal …
Neutralizing monoclonal antibodies against highly pathogenic coronaviruses
R Xiang, Y Wang, L Wang, X Deng, S Huo… - Current Opinion in …, 2022 - Elsevier
The pandemic of Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory
syndrome 2 coronavirus (SARS-CoV-2) is a continuing worldwide threat to human health …
syndrome 2 coronavirus (SARS-CoV-2) is a continuing worldwide threat to human health …
Engineering a “muco‐trapping” ACE2‐immunoglobulin hybrid with picomolar affinity as an inhaled, pan‐variant immunotherapy for COVID‐19
Soluble angiotensin‐converting enzyme 2 (ACE2) can act as a decoy molecule that
neutralizes severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) by blocking …
neutralizes severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) by blocking …
Development of an efficient method for selection of stable cell pools for protein expression and surface display with Expi293F cells
Compare with transient expression, stable cell lines generally have higher productivity and
better quality for protein expression. However, selection of stable cell line is time‐consuming …
better quality for protein expression. However, selection of stable cell line is time‐consuming …
COVID-19 diverse outcomes: Aggravated reinfection, type I interferons and antibodies
RCMC Silva, C Bandeira-Melo, HAP Neto, AM Vale… - Medical hypotheses, 2022 - Elsevier
SARS-CoV-2 infection intrigued medicine with diverse outcomes ranging from asymptomatic
to severe acute respiratory syndrome (SARS) and death. After more than two years of …
to severe acute respiratory syndrome (SARS) and death. After more than two years of …
Antibody libraries as tools to discover functional antibodies and receptor pleiotropism
CW Lin, RA Lerner - International Journal of Molecular Sciences, 2021 - mdpi.com
Most antibodies currently in use have been selected based on their binding affinity.
However, nowadays, antibodies that can not only bind but can also alter the function of cell …
However, nowadays, antibodies that can not only bind but can also alter the function of cell …
The longitudinal analysis of convergent antibody VDJ regions in SARS-coV-2-positive patients using RNA-seq
KJ Liu, MA Zelazowska, KM McBride - Viruses, 2023 - mdpi.com
Severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) is an ongoing
pandemic that continues to evolve and reinfect individuals. To understand the convergent …
pandemic that continues to evolve and reinfect individuals. To understand the convergent …
3D Bioprinted Neural‐Like Tissue as a Platform to Study Neurotropism of Mouse‐Adapted SARS‐CoV‐2
BAG de Melo, MV Mundim, RMR Lemes… - Advanced …, 2022 - Wiley Online Library
The effects of neuroinvasion by severe acute respiratory syndrome coronavirus 2 (SARS‐
CoV‐2) become clinically relevant due to the numerous neurological symptoms observed in …
CoV‐2) become clinically relevant due to the numerous neurological symptoms observed in …