[HTML][HTML] Inflammasomes: a rising star on the horizon of COVID-19 pathophysiology

M Wang, F Yu, W Chang, Y Zhang, L Zhang… - Frontiers in …, 2023 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a contagious respiratory
virus that is the cause of the coronavirus disease 2019 (COVID-19) pandemic which has …

Autoimmunity and SARS‐CoV‐2 infection: Unraveling the link in neurological disorders

D Latorre - European Journal of Immunology, 2022 - Wiley Online Library
Abstract According to the World Health Organization, severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2) has already infected more than 400 million people and …

mRNA vaccines against SARS-CoV-2 induce comparably low long-term IgG Fc galactosylation and sialylation levels but increasing long-term IgG4 responses …

JS Buhre, T Pongracz, I Künsting, AS Lixenfeld… - Frontiers in …, 2023 - frontiersin.org
Background The new types of mRNA-containing lipid nanoparticle vaccines BNT162b2 and
mRNA-1273 and the adenovirus-based vaccine AZD1222 were developed against SARS …

Cytokine storm signature in patients with moderate and severe COVID-19

O Kalinina, A Golovkin, E Zaikova, A Aquino… - International Journal of …, 2022 - mdpi.com
Hypercytokinemia, found in SARS-CoV-2 infection, contributes to multiple organ
dysfunctions with acute respiratory distress syndrome, shock etc. The aim of this study was …

Mitigation of influenza-mediated inflammation by immunomodulatory matrix-bound nanovesicles

RJ Crum, BR Huckestien, G Dwyer, L Mathews… - Science …, 2023 - science.org
Cytokine storm describes a life-threatening, systemic inflammatory syndrome characterized
by elevated levels of proinflammatory cytokines and immune cell hyperactivation associated …

Serum biomarkers associated with SARS-CoV-2 severity

F de Morais Batista, MAM Puga, PV da Silva… - Scientific Reports, 2022 - nature.com
Immunity with SARS-CoV-2 infection during the acute phase is not sufficiently well
understood to differentiate mild from severe cases and identify prognostic markers. We …

Liquid biomarkers of macrophage dysregulation and circulating spike protein illustrate the biological heterogeneity in patients with post‐acute sequelae of COVID‐19

C Schultheiß, E Willscher, L Paschold… - Journal of Medical …, 2023 - Wiley Online Library
Post‐acute sequelae of COVID‐19 (PASC) are long‐term consequences of SARS‐CoV‐2
infection that can substantially impair the quality of life. Underlying mechanisms ranging …

[HTML][HTML] Comparison of lung-homing receptor expression and activation profiles on NK cell and T cell subsets in COVID-19 and influenza

D Brownlie, I Rødahl, R Varnaite, H Asgeirsson… - Frontiers in …, 2022 - frontiersin.org
Respiratory viral infections with SARS-CoV-2 and influenza viruses commonly induce a
strong infiltration of immune cells into the human lung, with potential detrimental effects on …

Coordinated innate and T-cell immune responses in mild COVID-19 patients from household contacts of COVID-19 cases during the first pandemic wave

A Aiello, A Grossi, S Meschi, M Meledandri… - Frontiers in …, 2022 - frontiersin.org
Objective To better define the immunopathogenesis of COVID-19, the present study aims to
characterize the early immune responses to SARS-CoV-2 infection in household contacts of …

[HTML][HTML] Interleukin-1β and interleukin-10 profiles and ratio in serum of COVID-19 patients and correlation with COVID-19 severity: a time series study

R Yudhawati, S Sakina, M Fitriah - International Journal of General …, 2022 - ncbi.nlm.nih.gov
Background Coronavirus disease-19 (COVID-19) can, in severe cases, lead to cytokine-
release syndrome owing to an excessive immune response. The release of different …