Severe sepsis and septic shock: review of the literature and emergency department management guidelines
Severe sepsis and septic shock are as common and lethal as other acute life-threatening
conditions that emergency physicians routinely confront such as acute myocardial infarction …
conditions that emergency physicians routinely confront such as acute myocardial infarction …
The economics of sepsis
AN Chalupka, D Talmor - Critical care clinics, 2012 - criticalcare.theclinics.com
Sepsis, severe sepsis, and the systemic inflammatory response syndrome (SIRS) are among
the most common reasons for admission to the intensive care unit (ICU). The global …
the most common reasons for admission to the intensive care unit (ICU). The global …
Serial procalcitonin predicts mortality in severe sepsis patients: results from the multicenter procalcitonin MOnitoring SEpsis (MOSES) study
P Schuetz, R Birkhahn, R Sherwin, AE Jones… - Critical care …, 2017 - journals.lww.com
Objectives: To prospectively validate that the inability to decrease procalcitonin levels by
more than 80% between baseline and day 4 is associated with increased 28-day all-cause …
more than 80% between baseline and day 4 is associated with increased 28-day all-cause …
Serum lactate as a predictor of mortality in emergency department patients with infection
STUDY OBJECTIVE: Little is known about risk-stratification biomarkers in emergency
department (ED) patients with suspected infection, and lactate is a biologically plausible …
department (ED) patients with suspected infection, and lactate is a biologically plausible …
Occult hypoperfusion and mortality in patients with suspected infection
Objective To determine, in the early stages of suspected clinically significant infection, the
independent relationship of the presenting venous lactate level to 28-day in-hospital …
independent relationship of the presenting venous lactate level to 28-day in-hospital …
Before–after study of a standardized hospital order set for the management of septic shock
ST Micek, N Roubinian, T Heuring, M Bode… - Critical care …, 2006 - journals.lww.com
Objective: To evaluate a standardized hospital order set for the management of septic shock
in the emergency department. Design: Before–after study design with prospective …
in the emergency department. Design: Before–after study design with prospective …
Implementation and outcomes of the Multiple Urgent Sepsis Therapies (MUST) protocol
Objectives: To describe the effectiveness of a comprehensive, interdisciplinary sepsis
treatment protocol with regard to both implementation and outcomes and to compare the …
treatment protocol with regard to both implementation and outcomes and to compare the …
Prospective external validation of the clinical effectiveness of an emergency department-based early goal-directed therapy protocol for severe sepsis and septic shock
AE Jones, A Focht, JM Horton, JA Kline - Chest, 2007 - Elsevier
Objective To determine the clinical effectiveness of implementing early goal-directed therapy
(EGDT) as a routine protocol in the emergency department (ED). Methods Prospective …
(EGDT) as a routine protocol in the emergency department (ED). Methods Prospective …
National study of emergency department visits for sepsis, 1992 to 2001
MC Strehlow, SD Emond, NI Shapiro… - Annals of emergency …, 2006 - Elsevier
STUDY OBJECTIVE: Epidemiologic data on emergency department (ED) patients with
sepsis are limited. Inpatient discharge records from 1979 to 2000 show that hospitalizations …
sepsis are limited. Inpatient discharge records from 1979 to 2000 show that hospitalizations …
Septic shock: a multidisciplinary response team and weekly feedback to clinicians improve the process of care and mortality
Objective: To evaluate the impact of weekly feedback to clinicians and the activation of a
sepsis response team on the process of care and hospital mortality in patients with severe …
sepsis response team on the process of care and hospital mortality in patients with severe …