The complexity of nicotinamide adenine dinucleotide (NAD), hypoxic, and aryl hydrocarbon receptor cell signaling in chronic kidney disease

CS Curran, JB Kopp - Journal of Translational Medicine, 2023 - Springer
Early-stage detection of chronic kidney diseases (CKD) is important to treatment that may
slow and occasionally halt CKD progression. CKD of diverse etiologies share similar …

A new era in the science and care of kidney diseases

C Zoccali, F Mallamaci, L Lightstone, V Jha… - Nature Reviews …, 2024 - nature.com
Notable progress in basic, translational and clinical nephrology research has been made
over the past five decades. Nonetheless, many challenges remain, including obstacles to …

Kidneys in heart failure: Impact of flozins

T Stompór, A Winiarska - Polish Heart Journal (Kardiologia …, 2023 - journals.viamedica.pl
Chronic kidney disease (CKD) and heart failure (HF) represent two modern diseases of
civilization and are closely related. According to the concept of cardio-renal and reno …

Role of symbiotic microbiota dysbiosis in the progression of chronic kidney disease accompanied with vascular calcification

M Sun, Y Fang, J Zheng, G Shi, J Guo… - Frontiers in …, 2024 - frontiersin.org
Background: Chronic kidney disease (CKD) is now globally recognized as a critical public
health concern. Vascular calcification (VC) represents a significant risk factor for …

Proprotein convertase subtilisin/kexin type 9 (PCSK9) and clinical outcomes in dialysis patients

C Torino, F Carbone, P Pizzini… - European Journal of …, 2024 - Wiley Online Library
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9), a factor accelerating the
degradation of LDL receptors, was associated with a gender‐dependent risk for …

Diagnosis of cardiovascular disease in patients with chronic kidney disease

C Zoccali, PB Mark, P Sarafidis, R Agarwal… - Nature Reviews …, 2023 - nature.com
Patients with chronic kidney disease (CKD) are at high risk of cardiovascular disease (CVD)
and cardiovascular death. Identifying and monitoring cardiovascular complications and …

The impact of population ageing on the burden of chronic kidney disease

NC Chesnaye, A Ortiz, C Zoccali, VS Stel… - Nature Reviews …, 2024 - nature.com
The burden of chronic kidney disease (CKD) and its risk factors are projected to rise in
parallel with the rapidly ageing global population. By 2050, the prevalence of CKD category …

Activation of PERK/eIF2α/ATF4/CHOP branch of endoplasmic reticulum stress response and cooperation between HIF-1α and ATF4 promotes Daprodustat-induced …

A Tóth, G Lente, DM Csiki, E Balogh, Á Szöőr… - Frontiers in …, 2024 - frontiersin.org
Introduction: Vascular calcification is accelerated in patients with chronic kidney disease
(CKD) and increases the risk of cardiovascular events. CKD is frequently associated with …

Gastrointestinal bleeding among 151 patients undergoing maintenance hemodialysis for end-stage renal failure: A 5-year follow-up study

S Nakayama, K Yamanouchi, A Takamori, T Goto… - Medicine, 2024 - journals.lww.com
Gastrointestinal bleeding is one serious complication of patients undergoing hemodialysis
with end-stage renal failure. The present study aimed to evaluate risks and clinical features …

Association of diabetes with cardiovascular calcification and all-cause mortality in end-stage renal disease in the early stages of hemodialysis: a retrospective cohort …

Q Li, P Li, Z Xu, ZY Lu, C Yang, J Ning - Cardiovascular Diabetology, 2024 - Springer
Background The main goal of this study was to examine how diabetes, cardiovascular
calcification characteristics and other risk factors affect mortality in end-stage renal disease …