Optimizing the use of cyclosporin in allogeneic stem cell transplantation

N Duncan, C Craddock - Bone marrow transplantation, 2006 - nature.com
Cyclosporin remains the most widely used immunosuppressive agent in patients
undergoing allogeneic stem cell transplantation (SCT). The increased awareness of the …

The use of therapeutic drug monitoring to optimise immunosuppressive therapy

SM Tsunoda, FT Aweeka - Clinical pharmacokinetics, 1996 - Springer
Most experience of the therapeutic drug monitoring of immunosuppressive agents has been
acquired in the field of solid organ transplantation; however, agents such as cyclosporin …

Relationship of tacrolimus (FK506) whole blood concentrations and efficacy and safety after HLA-identical sibling bone marrow transplantation

JR Wingard, RA Nash, D Przepiorka… - Biology of Blood and …, 1998 - tctjournal.org
A randomized clinical trial comparing tacrolimus with cyclosporine, both with short-course
methotrexate, as prophylaxis against graft-vs.-host disease (GVHD) in allogeneic HLA …

[HTML][HTML] Impact of cyclosporine-A concentration on the incidence of severe acute graft-versus-host disease after allogeneic stem cell transplantation

F Malard, RM Szydlo, E Brissot, P Chevallier… - Biology of blood and …, 2010 - Elsevier
This single-center retrospective study analyzed 85 consecutive patients who underwent
allogeneic stem cell transplantation (allo-SCT) with the aim to assess whether there is a …

Relationship of mycophenolic acid exposure to clinical outcome after hematopoietic cell transplantation

P Jacobson, J Rogosheske, JN Barker… - Clinical …, 2005 - Wiley Online Library
Mycophenolate mofetil is used increasingly to provide immunosuppression after
nonmyeloablative allogeneic hematopoietic cell transplantation. There is wide variability in …

[HTML][HTML] Association between calcineurin inhibitor blood concentrations and outcomes after allogeneic hematopoietic cell transplantation

R Ram, B Storer, M Mielcarek, BM Sandmaier… - Biology of Blood and …, 2012 - Elsevier
To determine whether calcineurin inhibitor (CNI) blood concentrations within the first month
after allogeneic hematopoietic cell transplantation (HCT) correlated with the incidence of …

Relationship between CsA trough blood concentration and severity of acute graft-versus-host disease after paediatric stem cell transplantation from matched-sibling or …

P Martin, N Bleyzac, G Souillet, C Galambrun… - Bone Marrow …, 2003 - nature.com
In order to determine optimal CsA trough blood concentrations (TBC) in the early post
transplantation period, we analysed relationships between TBC and acute graft-versus-host …

Impact of cyclosporine A concentration on acute graft‐vs‐host disease incidence after haploidentical hematopoietic cell transplantation

N Stocker, R Dulery, G Battipaglia… - European journal of …, 2019 - Wiley Online Library
Objectives This retrospective study analyzed the impact of early cyclosporine A (CsA)
initiation (day− 3) on the risk of acute graft‐vs‐host disease (aGvHD) after haploidentical …

Statement of current majority practices in graft-versus-host disease prophylaxis and treatment in children

C Peters, M Minkov, H Gadner, T Klingebiel… - Bone Marrow …, 2000 - nature.com
Great variations exist in the prophylaxis and treatment of GVHD in children undergoing
allogeneic stem cell transplantation (SCT). The EBMT Working Party Paediatric Diseases …

Clinical and pharmacological risk factors for acute graft-versus-host disease after paediatric bone marrow transplantation from matched-sibling or unrelated donors

P Martin, N Bleyzac, G Souillet, C Galambrun… - Bone marrow …, 2003 - nature.com
The aim of this study was to identify the risk factors for acute graft-versus-host disease
(aGVHD) in children transplanted from a matched-sibling donor (MSD) or an unrelated …