Translational bioinformatics for human reproductive biology research: examples, opportunities and challenges for a future reproductive medicine

K Liu, Y Zhang, C Martin, X Ma, B Shen - International Journal of …, 2022 - mdpi.com
Since 1978, with the first IVF (in vitro fertilization) baby birth in Manchester (England), more
than eight million IVF babies have been born throughout the world, and many new …

Data Science Opportunities To Improve Radiotherapy Planning and Clinical Decision Making

JO Deasy - Seminars in Radiation Oncology, 2024 - Elsevier
Radiotherapy aims to achieve a high tumor control probability while minimizing damage to
normal tissues. Personalizing radiotherapy treatments for individual patients, therefore …

Breast cancer prognosis through the use of multi-modal classifiers: current state of the art and the way forward

A Mathur, N Arya, K Pasupa, S Saha… - Briefings in …, 2024 - academic.oup.com
We present a survey of the current state-of-the-art in breast cancer detection and prognosis.
We analyze the evolution of Artificial Intelligence-based approaches from using just uni …

Developing lung cancer post-diagnosis system using pervasive data analytic framework

MS Pethuraj, B bin Mohd Aboobaider… - Computers and Electrical …, 2023 - Elsevier
The data from lung cancer patients using wearable sensors and clinical assessments after
observation is available to predict the disease's recurrence. In recurrence prediction …

vWCluster: Vector-valued optimal transport for network based clustering using multi-omics data in breast cancer

J Zhu, JH Oh, JO Deasy, AR Tannenbaum - Plos one, 2022 - journals.plos.org
In this paper, we present a network-based clustering method, called vector Wasserstein
clustering (vWCluster), based on the vector-valued Wasserstein distance derived from …

ETS1 deficiency in macrophages suppresses colorectal cancer progression by reducing the F4/80+TIM4+ macrophage population

Y Cao, A Guo, M Li, X Ma, X Bian, YR Chen… - …, 2024 - academic.oup.com
Tumor-associated macrophages (TAMs) take on pivotal and complex roles in the tumor
microenvironment (TME); however, their heterogeneity in the TME remains incompletely …

Wasserstein HOG: Local Directionality Extraction via Optimal Transport

J Zhu, H Veeraraghavan, J Jiang, JH Oh… - IEEE transactions on …, 2023 - ieeexplore.ieee.org
Directionally sensitive radiomic features including the histogram of oriented gradient (HOG)
have been shown to provide objective and quantitative measures for predicting disease …

MicroRNA interactome multiomics characterization for cancer research and personalized medicine: an expert review

KJ Sindhu, N Venkatesan… - OMICS: A Journal of …, 2021 - liebertpub.com
MicroRNAs (miRNAs) that are mutually modulated by their interacting partners (interactome)
are being increasingly noted for their significant role in pathogenesis and treatment of …

Cancer Informatics for Cancer Centers: Sharing Ideas on How to Build an Artificial Intelligence–Ready Informatics Ecosystem for Radiation Oncology

DS Bitterman, MF Gensheimer, D Jaffray… - JCO clinical cancer …, 2023 - ascopubs.org
In August 2022, the Cancer Informatics for Cancer Centers brought together cancer
informatics leaders for its biannual symposium, Precision Medicine Applications in Radiation …

SIG: Graph-Based Cancer Subtype Stratification With Gene Mutation Structural Information

C Zhang, W Li, M Deng, Y Jiang, X Cui… - … /ACM Transactions on …, 2024 - ieeexplore.ieee.org
Somatic tumors have a high-dimensional, sparse, and small sample size nature, making
cancer subtype stratification based on somatic genomic data a challenge. Current methods …