In adult mammals, massive sudden loss of cardiomyocytes after infarction overwhelms the
limited regenerative capacity of the myocardium, resulting in the formation of a collagen …

This review attempts to cover the implication of the toll-like receptors (TLRs) in controlling
immune functions with emphasis on their significance, function, regulation and expression …

First isolated from Cannabis in 1940 by Roger Adams, the structure of CBD was not
completely elucidated until 1963. Subsequent studies resulted in the pronouncement that …

Background—Inflammation plays a key role in the pathophysiology of myocardial
ischemia/reperfusion (I/R) injury; however, the mechanism by which myocardial I/R induces …

Since the initial description of the phenomenon by Jennings et al 50 years ago, our
understanding of the underlying mechanisms of reperfusion injury has grown significantly …

Introduction• TLR signalling• Endogenous TLR ligands• Biological significance of signalling
triggered by endogenous TLR ligands‐Ischemia and reperfusion injury‐Tissue repair and …

Myocardial ischemia reperfusion injury contributes to adverse cardiovascular outcomes after
myocardial ischemia, cardiac surgery or circulatory arrest. Primarily, no blood flow to the …

Injury caused by oxidative stress occurs in many clinical scenarios involving ischemia and
reperfusion such as organ transplantation, hemorrhagic shock (HS), myocardial infarction …

Recent studies suggest that the heart possesses an innate immune system that is intended
to delimit tissue injury, as well as orchestrate homoeostatic responses, within the heart. The …

Hyperglycemia, a commonly exhibited metabolic disorder in critically ill patients, activates
the body's inflammatory defense mechanism, causing the waterfall release of numerous …