[HTML][HTML] T cell memory: understanding COVID-19

NN Jarjour, D Masopust, SC Jameson - Immunity, 2021 - cell.com
As the SARS-CoV-2 pandemic has progressed, increasing attention has focused on
establishing natural and vaccine-induced immunity against this coronavirus and the …

[HTML][HTML] The SARS-CoV-2 B. 1.1. 529 Omicron virus causes attenuated infection and disease in mice and hamsters

M Diamond, P Halfmann, T Maemura… - Research …, 2021 - ncbi.nlm.nih.gov
Despite the development and deployment of antibody and vaccine countermeasures, rapidly-
spreading SARS-CoV-2 variants with mutations at key antigenic sites in the spike protein …

The role of viral infections in the onset of autoimmune diseases

B Sundaresan, F Shirafkan, K Ripperger, K Rattay - Viruses, 2023 - mdpi.com
Autoimmune diseases (AIDs) are the consequence of a breach in immune tolerance,
leading to the inability to sufficiently differentiate between self and non-self. Immune …

SARS-CoV-2 B. 1.1. 7 (alpha) and B. 1.351 (beta) variants induce pathogenic patterns in K18-hACE2 transgenic mice distinct from early strains

P Radvak, HJ Kwon, M Kosikova… - Nature …, 2021 - nature.com
SARS-CoV-2 variants of concern (VOC) B. 1.1. 7 (alpha) and B. 1.351 (beta) show increased
transmissibility and enhanced antibody neutralization resistance. Here we demonstrate in …

SARS-CoV-2 disease severity and transmission efficiency is increased for airborne compared to fomite exposure in Syrian hamsters

JR Port, CK Yinda, IO Owusu, M Holbrook… - Nature …, 2021 - nature.com
Transmission of SARS-CoV-2 is driven by contact, fomite, and airborne transmission. The
relative contribution of different transmission routes remains subject to debate. Here, we …

Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants

Z Zhao, Y Xie, B Bai, C Luo, J Zhou, W Li… - Nature …, 2023 - nature.com
Abstract Multiple SARS-CoV-2 Omicron sub-variants, such as BA. 2, BA. 2.12. 1, BA. 4, and
BA. 5, emerge one after another. BA. 5 has become the dominant strain worldwide …

Animal models for COVID-19: advances, gaps and perspectives

C Fan, Y Wu, X Rui, Y Yang, C Ling, S Liu… - Signal transduction and …, 2022 - nature.com
Abstract COVID-19, caused by SARS-CoV-2, is the most consequential pandemic of this
century. Since the outbreak in late 2019, animal models have been playing crucial roles in …

The importance of animal models in biomedical research: current insights and applications

A Domínguez-Oliva, I Hernández-Ávalos… - Animals, 2023 - mdpi.com
Simple Summary The present review highlights and examines the importance of animal
models in relevant topics concerning current human and animal health. Over the past five …

Interfering with interferons: A critical mechanism for critical COVID-19 pneumonia

HC Su, H Jing, Y Zhang… - Annual Review of …, 2023 - annualreviews.org
Infection with SARS-CoV-2 results in clinical outcomes ranging from silent or benign
infection in most individuals to critical pneumonia and death in a few. Genetic studies in …

The olfactory nerve is not a likely route to brain infection in COVID-19: a critical review of data from humans and animal models

R Butowt, N Meunier, B Bryche, CS von Bartheld - Acta neuropathologica, 2021 - Springer
One of the most frequent symptoms of COVID-19 is the loss of smell and taste. Based on the
lack of expression of the virus entry proteins in olfactory receptor neurons, it was originally …