3D bioprinted organ‐on‐chips
S Rahmani Dabbagh, M Rezapour Sarabi… - …, 2023 - Wiley Online Library
Abstract Organ‐on‐a‐chip (OOC) platforms recapitulate human in vivo‐like conditions more
realistically compared to many animal models and conventional two‐dimensional cell …
realistically compared to many animal models and conventional two‐dimensional cell …
Development and deployment of COVID-19 vaccines for those most vulnerable
WC Koff, T Schenkelberg, T Williams… - Science translational …, 2021 - science.org
Development of safe and effective COVID-19 vaccines is a global priority and the best hope
for ending the COVID-19 pandemic. Remarkably, in less than 1 year, vaccines have been …
for ending the COVID-19 pandemic. Remarkably, in less than 1 year, vaccines have been …
[HTML][HTML] Global public health security and justice for vaccines and therapeutics in the COVID-19 pandemic
Abstract A Lancet Commission for COVID-19 task force is shaping recommendations to
achieve vaccine and therapeutics access, justice, and equity. This includes ensuring safety …
achieve vaccine and therapeutics access, justice, and equity. This includes ensuring safety …
[HTML][HTML] An inhaled bioadhesive hydrogel to shield non-human primates from SARS-CoV-2 infection
The surge of fast-spreading SARS-CoV-2 mutated variants highlights the need for fast,
broad-spectrum strategies to counteract viral infections. In this work, we report a physical …
broad-spectrum strategies to counteract viral infections. In this work, we report a physical …
Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses
Globally, there is an urgency to develop effective, low-cost therapeutic interventions for
coronavirus disease 2019 (COVID-19). We previously generated the stable and ultrapotent …
coronavirus disease 2019 (COVID-19). We previously generated the stable and ultrapotent …
[HTML][HTML] Accelerated evolution of SARS-CoV-2 in free-ranging white-tailed deer
The zoonotic origin of the COVID-19 pandemic virus highlights the need to fill the vast gaps
in our knowledge of SARS-CoV-2 ecology and evolution in non-human hosts. Here, we …
in our knowledge of SARS-CoV-2 ecology and evolution in non-human hosts. Here, we …
[HTML][HTML] The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential …
CEZ Chan, SGK Seah, DH Chye, S Massey, M Torres… - PLoS …, 2021 - journals.plos.org
Although SARS-CoV-2-neutralizing antibodies are promising therapeutics against COVID-
19, little is known about their mechanism (s) of action or effective dosing windows. We report …
19, little is known about their mechanism (s) of action or effective dosing windows. We report …
miRNAs; a novel strategy for the treatment of COVID‐19
H Ying, M Ebrahimi, M Keivan… - Cell biology …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is the seventh member of the bat severe
acute respiratory syndrome family. COVID‐19 can fuse their envelopes with the host cell …
acute respiratory syndrome family. COVID‐19 can fuse their envelopes with the host cell …
Innate immune cell activation causes lung fibrosis in a humanized model of long COVID
L Cui, Z Fang, CM De Souza, T Lerbs… - Proceedings of the …, 2023 - National Acad Sciences
COVID-19 remains a global pandemic of an unprecedented magnitude with millions of
people now developing “COVID lung fibrosis.” Single-cell transcriptomics of lungs of patients …
people now developing “COVID lung fibrosis.” Single-cell transcriptomics of lungs of patients …
[HTML][HTML] SARS-CoV-2 infection in the Syrian hamster model causes inflammation as well as type I interferon dysregulation in both respiratory and non-respiratory …
ME Francis, U Goncin, A Kroeker, C Swan… - PLoS …, 2021 - journals.plos.org
COVID-19 (coronavirus disease 2019) caused by SARS-CoV-2 (severe acute respiratory
syndrome coronavirus 2) infection is a disease affecting several organ systems. A model that …
syndrome coronavirus 2) infection is a disease affecting several organ systems. A model that …